AF/LE Purified Anti-Mouse CD3ε Antibody[145-2C11]
Price:
Size:
500μg
50μg
1mg
- 应用性: FCM;Activ
- 亚型: Armenian Hamster IgG
- 宿主: Armenian Hamster
Background | CD3ε is a 20 kD transmembrane protein, also known as CD3 or T3. It is a member of the Ig superfamily and primarily expressed on T cells, NK-T cells, and at different levels on thymocytes during T cell differentiation. CD3ε forms a TCR complex by associating with the CD3δ, γ and ζ chains, as well as the TCR α/β or γ/δ chains. CD3 plays a critical role in TCR signal transduction, T cell activation, and antigen recognition by binding the peptide/MHC antigen complex. |
Alternate Names | T-cell surface glycoprotein CD3 epsilon chain;CD3E;T-cell surface antigen T3/Leu-4 epsilon chain;CD3e;CD3E;T3E; |
Swissprot | |
Gene ID | |
Clone No | |
Host | Armenian Hamster |
Reactivity | Mouse |
Application | |
Isotype | Armenian Hamster IgG |
Isotype Control | |
Conjugation | None (AF/LE) |
Storage Buffer | 0.2 μm filtered in PBS, pH 7.2. Azide Free (AF)/Low Endotoxin (LE): Contains no stabilizers or preservatives. Endotoxin level is < 2 EU/mg as Determined by LAL gel clotting assay. |
Storage | This product can be stored at 2-8°C for 12 months. Do not freeze. |
Expiration date | 12个月 |
Shipping |
冰袋 |
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Breast cancer cells promote CD169+ macrophage-associated immunosuppression through JAK2-mediated PD-L1 upregulation on macrophages
IF: 3.361Journal:INTERNATIONAL IMMUNOPHARMACOLOGY
Q1:Is CD3ε CD3?
Yes, it is. CD3 consists of 5 different chains, namely gamma, delta, epsilon, zeta, and eta chains. Almost all anti-CD3 monoclonal antibodies target the epsilon chain, which only expressed in T cells normally.