PE/Cyanine5.5 Anti-Rat CD8a Antibody[OX-8]
Price:
Size:
100Tests
50Tests
100Tests×2
- 应用性: FCM
- 亚型: Mouse IgG1, κ
- 宿主: Mouse
Background | CD8a is a 32 kD glycoprotein also known as T8, Lyt2, Ly-2, and CD8α. CD8a is a member of the immunoglobulin superfamily expressed on most thymocytes, subset of mature T cells, most NK cells, macrophages, and some activated CD4+ T cells (not resting). CD8a forms heterodimers with the CD8β chain (CD8b) on the surface of most thymocytes, while mature peripheral T lymphocytes express almost exclusively the CD8 αβ heterodimer. Intestinal intraepithelial lymphocytes express CD8a without CD8b. CD8 is an antigen co-receptor on T cells that interacts with MHC class I on antigen-presenting cells or epithelial cells. CD8 participates in T cell activation through its association with the T cell receptor complex and protein tyrosine kinase lck (p56lck). |
Alternate Names | T-cell surface glycoprotein CD8 alpha chain;CD8A;T-lymphocyte differentiation antigen T8/Leu-2;MAL; |
Swissprot | |
Gene ID | |
Clone No | |
Host | Mouse |
Reactivity | Rat |
Application | |
Isotype | Mouse IgG1, κ |
Isotype Control | |
Conjugation | PE/Cyanine 5.5 |
Conjugation Information | PE/Cyanine5.5 is designed to be excited by the Blue (488 nm), Green (532 nm) and yellow-green (561 nm) lasers and detected using an optical filter centered near 690 nm (e.g., a 690/50 nm bandpass filter). |
Spectrum | |
Storage Buffer | Phosphate buffered solution, pH 7.2, containing 0.09% sodium azide and 1% BSA. |
Storage | This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze. |
Expiration date | 12个月 |
Shipping |
冰袋 |
Rat splenocytes are stained with PE/Cyanine5.5 Anti-Rat CD8a Antibody[OX-8] (filled gray histogram) or PE/Cyanine5.5 Mouse IgG1, κ Isotype Control (empty black histogram).
E-AB-F1098C | FITC Anti-Rat CD8a Antibody[OX-8] | 100Tests , 50Tests , 100Tests×2 |
E-AB-F1098D | PE Anti-Rat CD8a Antibody[OX-8] | 100Tests , 50Tests , 100Tests×2 |
E-AB-F1098E | APC Anti-Rat CD8a Antibody[OX-8] | 100Tests , 50Tests , 100Tests×2 |
E-AB-F1098H | PE/Cyanine7 Anti-Rat CD8a Antibody[OX-8] | 100Tests , 50Tests , 100Tests×2 |
E-AB-F1098L | Elab Fluor® 488 Anti-Rat CD8a Antibody[OX-8] | 100Tests , 50Tests , 100Tests×2 |
E-AB-F1098UC | FITC Anti-Rat CD8a Antibody[OX-8] | 100μg , 25μg |
E-AB-F1098UD | PE Anti-Rat CD8a Antibody[OX-8] | 100μg , 25μg |
E-AB-F1098UE | APC Anti-Rat CD8a Antibody[OX-8] | 100μg , 25μg |
E-AB-F1098UH | PE/Cyanine7 Anti-Rat CD8a Antibody[OX-8] | 100μg , 25μg |
E-AB-F1098UI | PE/Cyanine5.5 Anti-Rat CD8a Antibody[OX-8] | 100μg , 25μg |
E-AB-F1098UL | Elab Fluor® 488 Anti-Rat CD8a Antibody[OX-8] | 100μg , 25μg |
Q1:Are CD8 and CD8α the same index?
Yes they are. CD8 and CD8α are widely used markers for identifying cytotoxic T lymphocytes (CTLs). CD8 plays an important role in mediating the recognition and excution funtions of CTLs. CD8α is a subunit of CD8 complex, which means the α chain, and it is quite important in the formation of the complex. CD8α chain not only participates in the binding with MHC-I molecules, but also regulates the activity of CTLs by interacting with other signal molecules. Therefore, the expression level and functional status of CD8α can be used for evaluating the activation and effection of CTLs, as well as CD8.