Biotin Anti-Mouse CD49b/pan-NK cells Antibody[DX5]
Price:
Size:
100μg
25μg
- 应用性: FCM
- 亚型: Rat IgM, κ
- 宿主: Rat
Background | DX5 antigen has been recently characterized as CD49b. It is a 150 kD integrin α chain also known as α2 integrin, VLA-2 α chain, and integrin α2 chain. CD49b non-covalently associates with CD29 (β1 integrin) to form the CD49b/CD29 complex known as VLA-2, a receptor for collagen and laminin. CD49b is expressed on platelets, the majority of NK cells, NKT cells, and a small subset of CD8+ T cells (this population can be significantly increased following viral infection). DX5 is used for the identification and isolation of NK cells, and is especially useful for identifying NK cells in mice lacking the NK1.1 antigen. |
Alternate Names | Integrin alpha-2;CD49 antigen-like family member B;Collagen receptor;Platelet membrane glycoprotein Ia;GPIa;VLA-2 subunit alpha;CD49b; |
Swissprot | |
Gene ID | |
Clone No | |
Host | Rat |
Reactivity | Mouse |
Application | |
Isotype | Rat IgM, κ |
Isotype Control | |
Conjugation | Biotin |
Storage Buffer | Phosphate buffered solution, pH 7.2, containing 0.09% sodium azide and 1% BSA. |
Storage | This product can be stored at 2-8°C for 12 months. Do not freeze. |
Expiration date | 12个月 |
Shipping |
冰袋 |
Q1:Is there any requirement for the mouse strain while identify of mouse NK cells?
For the identification of mouse NK cells, CD3-CD49b+ or CD3-NK1.1+ should be selected according to the mouse strain, such as CD49b(DX5) for BALB/c mice and NK1.1 for C57BL/6 mice. CD49b is recommended for other strains.