Elab Fluor® 488 Anti-Human CD192/CCR2 Antibody[K036C2]
Price:
Size:
100Tests
20Tests
100Tests×2
- 应用性： FCM
- 亚型： Mouse IgG2a, κ
- 宿主： Mouse
| Background | CCR2 is a chemokine receptor that binds monocyte chemoattractant proteins (MCP-1, 2, 3 and 4). Two spliced variants were initially described for CCR2 (CCR2A and CCR2B). These variants differ in their terminal carboxyl tails. Monocyte adhesion to the arterial endothelium and subsequent migration into the intima are central events in the pathogenesis of atherosclerosis. CCR2 and MCP-1 have been associated to atherosclerotic plaques. MCP-1 is induced by modified-LDL in endothelial cells and may trigger firm adhesion of monocytes to vascular endothelium under flow conditions. Local overexpression of MCP-1 at vessel walls induces infiltration of macrophages and formation of atherosclerotic lesions. Obesity induces an inflammatory state that is implicated in many clinically important complications, including insulin resistance, diabetes, atherosclerosis, and non-alcoholic fatty liver disease. CCR2 influences the development of obesity and associated adipose tissue inflammation. |
| Alternate Names | CKR2;CCR2A;CCR2B;CKR2A;CKR2B;CMKBR2;MCP-1-R;CC-CKR-2 |
| Swissprot | |
| Gene ID | |
| Clone No | |
| Host | Mouse |
| Reactivity | Human |
| Application | |
| Isotype | Mouse IgG2a, κ |
| Isotype Control | |
| Conjugation | Elab Fluor®488 |
| Conjugation Information | Elab Fluor® 488 is designed to be excited by the Blue laser (488 nm) and detected using an optical filter centered near 520 nm (e.g., a 525/40 nm bandpass filter). |
| Spectrum |  |
| Storage Buffer | Phosphate buffered solution, pH 7.2, containing 0.09% sodium azide and 1% BSA. |
| Storage | This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze. |
| Expiration date | 12个月 |
| Shipping |
冰袋 |
Staining of normal human peripheral blood cells with Elab Fluor? 488 Anti-Human CD192/CCR2 Antibody[K036C2] (filled gray histogram) or Elab Fluor? 488 Mouse IgG2a, κ Isotype Control (empty black histogram). Cells in the monocytes gate were used for analysis.
| E-AB-F1385D | PE Anti-Human CD192/CCR2 Antibody[K036C2] | 100Tests , 20Tests , 100Tests×2 |
| E-AB-F1385E | APC Anti-Human CD192/CCR2 Antibody[K036C2] | 100Tests , 20Tests , 100Tests×2 |
| E-AB-F1385J | PerCP/Cyanine5.5 Anti-Human CD192/CCR2 Antibody[K036C2] | 100Tests , 20Tests , 100Tests×2 |
