Elab Fluor® 647 Anti-Human CD11b Antibody[ICRF44]
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- 应用性: FCM
- 亚型: Mouse IgG1, κ
- 宿主: Mouse
Background | CD11b is a 165-170 kD type I transmembrane glycoprotein also known as αMintegrin, Mac-1, CR3, and C3biR. CD11b non-covalently associates with integrin β2(CD18) and is expressed on granulocytes, monocytes/macrophages, dendritic cells, NK cells, and subsets of T and B cells. CD11b/CD18 is critical for the transendothelial migration of monocytes and neutrophils. It is also involved in granulocyte adhesion, phagocytosis, and neutrophil activation. CD11b/CD18 interacts with ICAM-1 (CD54), ICAM-2 (CD102), ICAM-4, CD14, CD23, heparin, iC3b, fibrinogen, and factor X. |
Alternate Names | Integrin alpha-M;Itgam;CD11 antigen-like family member B;CR-3 alpha chain;Leukocyte adhesion receptor MO1;CD11b; |
Swissprot | |
Gene ID | |
Clone No | |
Host | Mouse |
Reactivity | Human |
Application | |
Isotype | Mouse IgG1, κ |
Isotype Control | |
Conjugation | Elab Fluor®647 |
Conjugation Information | Elab Fluor® 647 is designed to be excited by the Red laser (627-640 nm) and detected using an optical filter centered near 670 nm (e.g., a 660/20 nm bandpass filter). |
Spectrum | |
Storage Buffer | Phosphate buffered solution, pH 7.2, containing 0.09% sodium azide and 1% BSA. |
Storage | This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze. |
Expiration date | 12个月 |
Shipping |
冰袋 |
E-AB-F1146C | FITC Anti-Human CD11b Antibody[ICRF44] | 100Tests , 20Tests , 100Tests×2 |
E-AB-F1146D | PE Anti-Human CD11b Antibody[ICRF44] | 100Tests , 20Tests , 100Tests×2 |
E-AB-F1146E | APC Anti-Human CD11b Antibody[ICRF44] | 100Tests , 20Tests , 100Tests×2 |
E-AB-F1146F | PerCP Anti-Human CD11b Antibody[ICRF44] | 100Tests , 20Tests , 100Tests×2 |
E-AB-F1146G | PE/Cyanine5 Anti-Human CD11b Antibody[ICRF44] | 100Tests , 20Tests , 100Tests×2 |
E-AB-F1146H | PE/Cyanine7 Anti-Human CD11b Antibody[ICRF44] | 100Tests , 20Tests , 100Tests×2 |
E-AB-F1146I | PE/Cyanine5.5 Anti-Human CD11b Antibody[ICRF44] | 100Tests , 20Tests , 100Tests×2 |
E-AB-F1146J | PerCP/Cyanine5.5 Anti-Human CD11b Antibody[ICRF44] | 100Tests , 20Tests , 100Tests×2 |
E-AB-F1146L | Elab Fluor® 488 Anti-Human CD11b Antibody[ICRF44] | 100Tests , 20Tests , 100Tests×2 |
E-AB-F1146S | Elab Fluor® Red 780 Anti-Human CD11b Antibody[ICRF44] | 100Tests , 20Tests , 100Tests×2 |
Q1:What are the recommendations for flow cytometry of mouse macrophages to detect M1 and M2 type macrophages?
As a recommandation, F4/80 and CD11b are always used for identyfing macrophages of mouse, and CD86 and CD206 can be used for a further seperation for M1 abd M2 respectively. Specific indicators can be determined according to the literature and experimental requirements.