FITC Anti-Human IL-17A Antibody[BL168]
Price:
Size:
100Tests
20Tests
100Tests×2
- 应用性: ICFCM
- 亚型: Mouse IgG1, κ
- 宿主: Mouse
Background | IL-17A is the founding member of the IL-17 family, a group of six structurally related pro-inflammatory cytokines. IL-17A, secreted by activated CD4+ Th17 cell subpopulation, elicits multiple biological activities on a variety of cells including: the induction of IL-6, IL-8, G-CSF, and PGE2 production in epithelial, endothelial or fibroblasts; the enhancement of surface expression of ICAM-1 in fibroblasts; activation of NF-κB and costimulation of T cell proliferation. Recent studies demonstrated that, in mice, activated IL-17-secreting CD4+ helper T cells (Th17 cells) mediate an autoimmune arthritis that clinically and immunologically resembles rheumatoid arthritis (RA). Human IL-17A shows 63%, 63%, and 72% amino acid sequence identity to rat IL-17A, mouse IL-17A, and a protein encoded by the ORF13 gene of herpesvirus Saimiri (HVS), respectively. |
Alternate Names | CTLA8; IL17;CTLA-8;IL 17A; |
Swissprot | |
Gene ID | |
Clone No | |
Host | Mouse |
Reactivity | Human |
Application | |
Isotype | Mouse IgG1, κ |
Isotype Control | |
Conjugation | FITC |
Conjugation Information | FITC is designed to be excited by the Blue laser (488 nm) and detected using an optical filter centered near 530 nm (e.g., a 525/40 nm bandpass filter). |
Spectrum | |
Storage Buffer | Phosphate buffered solution, pH 7.2, containing 0.09% sodium azide and 1% BSA. |
Storage | This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze. |
Expiration date | 12个月 |
Shipping |
冰袋 |
HEK293T cells transiently transfected with pcDNA3.1 plasmid encoding Human IL-17A gene are stained with FITC Anti-Human IL-17A Antibody (filled gray histogram) or FITC Mouse IgG1, κ lsotype Control (empty black histogram).
E-AB-F1173D | PE Anti-Human IL-17A Antibody[BL168] | 100Tests , 20Tests , 100Tests×2 |
E-AB-F1173E | APC Anti-Human IL-17A Antibody[BL168] | 100Tests , 20Tests , 100Tests×2 |