FITC Anti-Mouse CD105 Antibody[MJ7/18]
Price:
Size:
100Tests
50Tests
100Tests×2
- 应用性: FCM
- 亚型: Rat IgG2a, κ
- 宿主: Rat
Background | CD105 is a 90 kD homodimeric type I integral membrane glycoprotein, also known as endoglin. It is expressed on endothelial cells (especially on angiogenic endothelial cells) and upregulated by hypoxia, activated monocytes, macrophages, bone marrow stromal cells, and some cytotrophoblasts. CD105 is a receptor for TGF-β1, TGF-β3 and modulates TGF-β signaling by interacting with TGF-β receptors I and/or II. CD105 also binds other growth factors such as actvin A, BMP-2, and BMP-7. CD105 has been show to be a useful marker for identifying proliferating endothelium involved in tumor angiogenesis and can be used for tumor imaging and prognosis, and has therapeutic potential for some solid tumors and other angiogenic diseases. |
Alternate Names | Endoglin;END;Eng; |
Swissprot | |
Gene ID | |
Clone No | |
Host | Rat |
Reactivity | Mouse |
Application | |
Isotype | Rat IgG2a, κ |
Isotype Control | |
Conjugation | FITC |
Conjugation Information | FITC is designed to be excited by the Blue laser (488 nm) and detected using an optical filter centered near 530 nm (e.g., a 525/40 nm bandpass filter). |
Spectrum | |
Storage Buffer | Phosphate buffered solution, pH 7.2, containing 0.09% sodium azide and 1% BSA. |
Storage | This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze. |
Expiration date | 12个月 |
Shipping |
冰袋 |
endothelial cells (bEnd.3) are stained with FITC Anti-Mouse CD105 Antibody[MJ7/18] (filled gray histogram) or FITC Rat IgG2a, κ Isotype Control (empty black histogram).
E-AB-F1233D | PE Anti-Mouse CD105 Antibody[MJ7/18] | 100Tests , 50Tests , 100Tests×2 |
E-AB-F1233E | APC Anti-Mouse CD105 Antibody[MJ7/18] | 100Tests , 50Tests , 100Tests×2 |
E-AB-F1233UD | PE Anti-Mouse CD105 Antibody[MJ7/18] | 100μg , 25μg |
E-AB-F1233UE | APC Anti-Mouse CD105 Antibody[MJ7/18] | 100μg , 25μg |