PE Anti-Mouse CD45.1 Antibody[A20]
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- 应用性: FCM
- 亚型: Mouse IgG2a, κ
- 宿主: Mouse
Background | CD45.1 is an alloantigen of CD45, expressed by Ly5.1 bearing mouse strains (e.g., RIII, SJL/J, STS/A, DA). CD45, a member of the protein tyrosine phosphatase (PTP) family, is a 180-240 kD glycoprotein expressed on all hematopoietic cells except mature erythrocytes and platelets. There are multiple isoforms in mice that play key roles in TCR and BCR signal transduction. These isoforms are very specific to the activation and maturation states of the cell as well as specific cell types. The primary ligands for CD45 are galectin-1, CD2, CD3, CD4, TCR, CD22, and Thy-1. |
Alternate Names | Ly-5;L-CA;T200;CD45;Ptprc; |
Gene ID | |
Clone No | |
Host | Mouse |
Reactivity | Mouse |
Application | |
Isotype | Mouse IgG2a, κ |
Isotype Control | |
Conjugation | PE |
Conjugation Information | PE is designed to be excited by the Blue (488 nm), Green (532 nm) and Yellow-Green (561 nm) lasers and detected using an optical filter centered near 575 nm (e.g., a 585/42 nm bandpass filter). |
Spectrum | |
Storage Buffer | Phosphate buffered solution, pH 7.2, containing 0.09% sodium azide and 1% BSA. |
Storage | This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze. |
Expiration date | 12个月 |
Shipping |
冰袋 |
E-AB-F1184C | FITC Anti-Mouse CD45.1 Antibody[A20] | 100Tests , 50Tests , 100Tests×2 |
E-AB-F1184D | PE Anti-Mouse CD45.1 Antibody[A20] | 100Tests , 50Tests , 100Tests×2 |
E-AB-F1184E | APC Anti-Mouse CD45.1 Antibody[A20] | 100Tests , 50Tests , 100Tests×2 |
E-AB-F1184Q | Elab Fluor® Violet 450 Anti-Mouse CD45.1 Antibody[A20] | 100Tests , 50Tests , 100Tests×2 |
E-AB-F1184UC | FITC Anti-Mouse CD45.1 Antibody[A20] | 100μg , 25μg |
E-AB-F1184UE | APC Anti-Mouse CD45.1 Antibody[A20] | 100μg , 25μg |
E-AB-F1184UQ | Elab Fluor® Violet 450 Anti-Mouse CD45.1 Antibody[A20] | 100μg , 25μg |
Q1:Is CD45.1/ CD45.2 CD45?
No, they are not. CD45.1 and CD45.2 are subtype marker forms on the surface of immune cells and belong to the CD45 (cluster of differentiation 45) family. CD45 is a receptor protein tyrosine phosphatase, widely expressed in a variety of immune cells, such as T cells, B cells, macrophages and so on. CD45 exists in several subtypes, including CD45.1 and CD45.2. These two subtypes are mainly determined by different alleles on the CD45 gene. In experiments, the introduction of alleles of CD45.1 or CD45.2 can be used to distinguish between cells of different origin. The mouse strains expressing CD45.1 include FVB, RIII, SJL/J, STS/A, DA, etc. The mouse strains expressing CD45.2 included AKR, BALB/c, CBA/Ca, CBA/J, C3H/He, C57BL, C57BR, C57L, C58, DBA/1, DBA/2, NZB, SWR, 129, etc.