Purified Anti-Mouse CD103 Antibody[M290]
Price:
Size:
100μg
25μg
- 应用性: FCM
- 亚型: Rat IgG2a, κ
- 宿主: Rat
Background | CD103 is a type I transmembrane glycoprotein known as αE integrin or Integrin αIEL chain. It belongs to the integrin family and is primarily found on intestinal intraepithelial lymphocytes (IEL). CD103 is also expressed on a subpopulation of lamina propria T cells, epithelial dendritic cells, lamina propria-derived dendritic cells, and a small subset of peripheral lymphocytes. T regulatory cells express high level of CD103. The CD103 expression on lymphocytes can be induced upon activation and TGF-β stimulation. In association with integrin β7, CD103 is expressed as αE/β7 heterodimer. Mature CD103 protein can be cleaved into 2 chains, a 150 kD (C-terminal) chain and a 25 kD (N-terminal) chain, which remain linked by disulfide bonds. CD103 binds to E-cadherin and mediates homing of lymphocytes to the intestinal epithelium. |
Alternate Names | Integrin alpha-E;Itgae;Integrin alpha M290;CD103; |
Swissprot | |
Gene ID | |
Clone No | |
Host | Rat |
Reactivity | Mouse |
Application | |
Isotype | Rat IgG2a, κ |
Isotype Control | |
Conjugation | Unconjugated |
Storage Buffer | Phosphate buffered solution, pH 7.2, containing 0.09% sodium azide. |
Storage | This product can be stored at 2-8°C for 12 months. Do not freeze. |
Expiration date | 12个月 |
Shipping |
冰袋 |