Purified Anti-Mouse CD161/NK1.1 Antibody[PK136]
Price:
Size:
100μg
25μg
- 应用性: FCM
- 亚型: Mouse IgG2a, κ
- 宿主: Mouse
Background | NK-1.1 surface antigen, also known as CD161b/CD161c and Ly-55, is encoded by the NKR-P1B/NKR-P1C gene. It is expressed on NK cells and NK-T cells in some mouse strains, including C57BL/6, FVB/N, and NZB, but not AKR, BALB/c, CBA/J, C3H, DBA/1, DBA/2, NOD, SJL, and 129. Expression of NKR-P1C antigen has been correlated with lysis of tumor cells in vitro and rejection of bone marrow allografts in vivo. NK-1.1 has also been shown to play a role in NK cell activation, IFN-γ production, and cytotoxic granule release. NK-1.1 and DX5 are commonly used as mouse NK cell markers. |
Alternate Names | Killer cell lectin-like receptor subfamily B member 1C;Klrb1c;CD161 antigen-like family member C;Ly-55c;CD161/NK1.1;NKR-P1.9;NKR-P1C;NKR-P1 40;CD161c; |
Swissprot | |
Gene ID | |
Clone No | |
Host | Mouse |
Reactivity | Mouse |
Application | |
Isotype | Mouse IgG2a, κ |
Isotype Control | |
Conjugation | Unconjugated |
Storage Buffer | Phosphate buffered solution, pH 7.2, containing 0.09% sodium azide. |
Storage | This product can be stored at 2-8°C for 12 months. Do not freeze. |
Expiration date | 12个月 |
Shipping |
冰袋 |
Q1:Is there any requirement for the mouse strain while identify of mouse NK cells?
For the identification of mouse NK cells, CD3-CD49b+ or CD3-NK1.1+ should be selected according to the mouse strain, such as CD49b(DX5) for BALB/c mice and NK1.1 for C57BL/6 mice. CD49b is recommended for other strains.