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Elab Fluor® 488 Anti-Mouse CD8a Antibody[53-6.7]

Price: ¥684 ¥384 ¥1032

Size:
100Tests 50Tests 100Tests×2
  • 应用性: FCM
  • 亚型: Rat IgG2a, κ
  • 宿主: Rat
Background
CD8, also known as Lyt-2, Ly-2, or T8, consists of disulfide-linked α and β chains that form the α(CD8a)/β(CD8b) heterodimer and α/α homodimer. CD8a is a 34 kD protein that belongs to the immunoglobulin family. The CD8 α/β heterodimer is expressed on the surface of most thymocytes and a subset of mature TCR α/β T cells. CD8 expression on mature T cells is non-overlapping with CD4. The CD8 α/α homodimer is expressed on a subset of γ/δ TCR-bearing T cells, NK cells, intestinal intraepithelial lymphocytes, and lymphoid dendritic cells. CD8 is an antigen co-receptor on T cells that interacts with MHC class I on antigen-presenting cells or epithelial cells. CD8 promotes T cell activation through its association with the TCR complex and protein tyrosine kinase lck.
Alternate Names
T-cell surface glycoprotein CD8 alpha chain;CD8A;T-lymphocyte differentiation antigen T8/Leu-2;MAL;
Swissprot
Gene ID
Clone No
Host
Rat
Reactivity
Mouse
Application
Isotype
Rat IgG2a, κ
Isotype Control
Conjugation
Elab Fluor®488
Conjugation Information
Elab Fluor® 488 is designed to be excited by the Blue laser (488 nm) and detected using an optical filter centered near 520 nm (e.g., a 525/40 nm bandpass filter).
Spectrum
Storage Buffer
Phosphate buffered solution, pH 7.2, containing 0.09% sodium azide and 1% BSA.
Storage
This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.
Expiration date
12个月
Shipping
冰袋
C57BL/6 murine splenocytes are stained with Elab Fluor® 488 Anti-Mouse CD8a Antibody (filled gray histogram). Unstained splenocytes (empty black histogram) are used as control.
E-AB-F11040 AF/LE Purified Anti-Mouse CD8a Antibody[53-6.7] 500μg , 50μg , 1mg
E-AB-F1104A Purified Anti-Mouse CD8a Antibody[53-6.7] 100μg , 25μg
E-AB-F1104B Biotin Anti-Mouse CD8a Antibody[53-6.7] 100μg , 25μg
E-AB-F1104C FITC Anti-Mouse CD8a Antibody[53-6.7] 100Tests , 50Tests , 100Tests×2
E-AB-F1104D PE Anti-Mouse CD8a Antibody[53-6.7] 100Tests , 50Tests , 100Tests×2
E-AB-F1104E APC Anti-Mouse CD8a Antibody[53-6.7] 100Tests , 50Tests , 100Tests×2
E-AB-F1104F PerCP Anti-Mouse CD8a Antibody[53-6.7] 100Tests , 50Tests , 100Tests×2
E-AB-F1104H PE/Cyanine7 Anti-Mouse CD8a Antibody[53-6.7] 100Tests , 50Tests , 100Tests×2
E-AB-F1104I PE/Cyanine5.5 Anti-Mouse CD8a Antibody[53-6.7] 100Tests , 50Tests , 100Tests×2
E-AB-F1104J PerCP/Cyanine5.5 Anti-Mouse CD8a Antibody[53-6.7] 100Tests , 50Tests , 100Tests×2
E-AB-F1104M Elab Fluor® 647 Anti-Mouse CD8a Antibody[53-6.7] 100Tests , 50Tests , 100Tests×2
E-AB-F1104P PE/Elab Fluor® 594 Anti-Mouse CD8a Antibody[53-6.7] 100Tests , 50Tests , 100Tests×2
E-AB-F1104Q Elab Fluor® Violet 450 Anti-Mouse CD8a Antibody[53-6.7] 100Tests , 50Tests , 100Tests×2
E-AB-F1104S Elab Fluor® Red 780 Anti-Mouse CD8a Antibody[53-6.7] 100Tests , 50Tests , 100Tests×2
E-AB-F1104UC FITC Anti-Mouse CD8a Antibody[53-6.7] 100μg , 25μg
E-AB-F1104UD PE Anti-Mouse CD8a Antibody[53-6.7] 100μg , 25μg
E-AB-F1104UE APC Anti-Mouse CD8a Antibody[53-6.7] 100μg , 25μg
E-AB-F1104UF PerCP Anti-Mouse CD8a Antibody[53-6.7] 100μg , 25μg
E-AB-F1104UH PE/Cyanine7 Anti-Mouse CD8a Antibody[53-6.7] 100μg , 25μg
E-AB-F1104UI PE/Cyanine5.5 Anti-Mouse CD8a Antibody[53-6.7] 100μg , 25μg
E-AB-F1104UJ PerCP/Cyanine5.5 Anti-Mouse CD8a Antibody[53-6.7] 100μg , 25μg
E-AB-F1104UL Elab Fluor® 488 Anti-Mouse CD8a Antibody[53-6.7] 100μg , 25μg
E-AB-F1104UM Elab Fluor® 647 Anti-Mouse CD8a Antibody[53-6.7] 100μg , 25μg
E-AB-F1104UP PE/Elab Fluor® 594 Anti-Mouse CD8a Antibody[53-6.7] 100μg , 25μg
E-AB-F1104UQ Elab Fluor® Violet 450 Anti-Mouse CD8a Antibody[53-6.7] 100μg , 25μg
E-AB-F1104US Elab Fluor® Red 780 Anti-Mouse CD8a Antibody[53-6.7] 100μg , 25μg

Q1:Are CD8 and CD8α the same index?

Yes they are. CD8 and CD8α are widely used markers for identifying cytotoxic T lymphocytes (CTLs). CD8 plays an important role in mediating the recognition and excution funtions of CTLs. CD8α is a subunit of CD8 complex, which means the α chain, and it is quite important in the formation of the complex. CD8α chain not only participates in the binding with MHC-I molecules, but also regulates the activity of CTLs by interacting with other signal molecules. Therefore, the expression level and functional status of CD8α can be used for evaluating the activation and effection of CTLs, as well as CD8.



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