Elab Fluor® 647 Anti-Human CD49d Antibody[BU49]
Price:
Size:
100Tests
20Tests
100Tests×2
- 应用性: FCM
- 亚型: Mouse IgG1, κ
- 宿主: Mouse
Background | CD49d is a 150 kD α integrin chain known as α4 integrin or VLA-4 α chain. It forms a heterodimer with either integrin β1 (α4β1, VLA-4) or β7 (α4β7). CD49d is expressed broadly on T lymphocytes, B lymphocytes, monocytes, thymocytes, eosinophils, basophils, mast cells, NK cells, dendritic cells, and some non-hematopoietic cells, but not on normal red blood cells, platelets or neutrophils. VLA-4 binds to VCAM-1 (CD106) and fibronectin. α4β7 is the receptor for VCAM-1 and MAdCAM-1. CD49d participates in mononuclear cell trafficking to endothelial sites of inflammation and has roles in cell-cell interactions and cell adhesion to extracellular matrices. CD49d is involved in lymphocyte migration, T cell activation, and hematopoietic stem cell differentiation. CD49d is a marker to isolate pure populations of Treg cells due to its absence on Foxp3+ cells. |
Alternate Names | Integrin alpha-4;ITGA4;CD49 antigen-like family member D;Integrin alpha-IV;VLA-4 subunit alpha;CD49d; |
Swissprot | |
Gene ID | |
Clone No | |
Host | Mouse |
Reactivity | Human |
Application | |
Isotype | Mouse IgG1, κ |
Isotype Control | |
Conjugation | Elab Fluor®647 |
Conjugation Information | Elab Fluor® 647 is designed to be excited by the Red laser (627-640 nm) and detected using an optical filter centered near 670 nm (e.g., a 660/20 nm bandpass filter). |
Spectrum | |
Storage Buffer | Phosphate buffered solution, pH 7.2, containing 0.09% sodium azide and 1% BSA. |
Storage | This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze. |
Expiration date | 12个月 |
Shipping |
冰袋 |
Human peripheral blood lymphocytes are stained with Elab Fluor® 647 Anti-Human CD49d Antibody (filled gray histogram). Unstained lymphocytes (empty black histogram) are used as control.
E-AB-F1040C | FITC Anti-Human CD49d Antibody[BU49] | 100Tests , 20Tests , 100Tests×2 |