Elab Fluor® 647 Anti-Mouse CD279/PD-1 Antibody[29F.1A12]
Price:
Size:
100μg
25μg
- 应用性: FCM
- 亚型: Rat IgG2a, κ
- 宿主: Rat
Background | CD279, also known as programmed death-1 (PD-1), is a 50-55 kD glycoprotein belonging to the CD28 family of the Ig superfamily. PD-1 is expressed on activated splenic T and B cells and thymocytes. It is induced on activated myeloid cells as well. PD-1 is involved in lymphocyte clonal selection and peripheral tolerance through binding its ligands, B7-H1 (PD-L1) and B7-DC (PD-L2). It has been reported that PD-1 and PD-L1 interactions are critical to positive selection and play a role in shaping the T cell repertoire. PD-L1 negative costimulation is essential for prolonged survival of intratesticular islet allografts. |
Alternate Names | PD-1; Programmed Death-1; |
Swissprot | |
Gene ID | |
Clone No | |
Host | Rat |
Reactivity | Mouse |
Application | |
Isotype | Rat IgG2a, κ |
Isotype Control | |
Conjugation | Elab Fluor®647 |
Conjugation Information | Elab Fluor® 647 is designed to be excited by the Red laser (627-640 nm) and detected using an optical filter centered near 670 nm (e.g., a 660/20 nm bandpass filter). |
Spectrum | |
Storage Buffer | Phosphate buffered solution, pH 7.2, containing 0.09% sodium azide and 1% BSA. |
Storage | This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze. |
Expiration date | 12个月 |
Shipping |
冰袋 |
Con-A stimulated C57BL/6 splenocytes (3 days) are stained with Elab Fluor® 647 Anti-Mouse CD279/PD-1 Antibody (filled gray histogram). Unstained splenocytes (empty black histogram) are used as control.