AF/LE Purified Anti-Human CD279/PD-1 Antibody[J110]
Price:
Size:
500μg
50μg
1mg
- 应用性: FCM
- 亚型: Mouse IgG1, κ
- 宿主: Mouse
Background | Programmed cell death 1 (PD-1), also known as CD279, is a 55 kD member of the immunoglobulin superfamily. CD279 contains the immunoreceptor tyrosine-based inhibitory motif (ITIM) in the cytoplasmic region and plays a key role in peripheral tolerance and autoimmune disease. CD279 is expressed predominantly on activated T cells, B cells, and myeloid cells. PD-L1 and PD-L2 are ligands of CD279 (PD-1) and are members of the B7 gene family. Evidence suggests overlapping functions for these two PD-1 ligands and their constitutive expression on some normal tissues and upregulation on activated antigen-presenting cells. Interaction of CD279 ligands results in inhibition of T cell proliferation and cytokine secretion. |
Alternate Names | PDCD1;PD1;Protein PD-1;hPD-1; |
Swissprot | |
Gene ID | |
Clone No | |
Host | Mouse |
Reactivity | Human |
Application | |
Isotype | Mouse IgG1, κ |
Isotype Control | |
Conjugation | None (AF/LE) |
Storage Buffer | 0.2 μm filtered in PBS, pH 7.2. Azide Free (AF)/Low Endotoxin (LE): Contains no stabilizers or preservatives. Endotoxin level is < 2 EU/mg as Determined by LAL gel clotting assay. |
Storage | This product can be stored at 2-8°C for 12 months. Do not freeze. |
Expiration date | 12个月 |
Shipping |
冰袋 |
E-AB-F1213A | Purified Anti-Human CD279/PD-1 Antibody[J110] | 100μg , 25μg |