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AF/LE Purified Anti-Mouse CD90.1/Thy1.1 Antibody[19E12]

Price: ¥1960 ¥600 ¥3560

Size:
500μg 50μg 1mg
  • 应用性: FCM
  • 亚型: Rat IgG2a, κ
  • 宿主: Rat
Background
CD90.1 is a 25-35 kD immunoglobulin superfamily member, also known as Thy-1. It is expressed on hematopoietic stem cells and neurons, all thymocytes, and peripheral T cells. CD90.1 is a glycosylphosphatidylinositol (GPI)-anchored membrane glycoprotein involved in signal transduction. CD90.1 is involved in costimulation of lymphocyte proliferation and activation, and hematopoietic stem cell differentiation. CD90.1 has been shown to interact with CD45.
Alternate Names
Thy-1.1 membrane glycoprotein;Thy1.1;Thy-1.1 antigen;CD90.1;Thy-1.1;
Gene ID
Clone No
Host
Rat
Reactivity
Mouse
Application
Isotype
Rat IgG2a, κ
Isotype Control
Conjugation
None (AF/LE)
Storage Buffer
0.2 μm filtered in PBS, pH 7.2. Azide Free (AF)/Low Endotoxin (LE): Contains no stabilizers or preservatives. Endotoxin level is < 2 EU/mg as Determined by LAL gel clotting assay.
Storage
This product can be stored at 2-8°C for 12 months. Do not freeze.
Expiration date
12个月
Shipping
冰袋

Q1:What is the difference between Mouse CD90 and CD90.1 and CD90.2?

CD90, also known as Thy1 (thymus cell antigen 1), is a mouse immune cell surface molecule. In mice, there are two main subtypes of CD90: CD90.1 and CD90.2. The difference between the two subtypes is due to allelic differences on the loci. CD90.1 and CD90.2 are expression variants controlled by different gene alleles. For example, in C57BL/6 mice, CD90.1 expression is regulated by the Ly5.2 locus, while CD90.2 is controlled by the Ly5.1 locus. Due to the differences in the loci of CD90.1 and CD90.2, these subtypes can be used for labeling in experiments to distinguish cells of different origin. By introducing the allele of CD90.1 or CD90.2, cells can be genetically labeled to identify, trace and quantitatively analyze cells of specific origin. CD90 can be expressed on hematopoietic stem cells, neurons, all thymic cells, and peripheral T cells. The mouse strains expressing CD90.1 included AKR, BDP, MA/MyJ, etc., and more mouse strains expressing CD90.2 included Balb/c, CBA/J, C3H/He, C57BL/-, DBA, NZB/-, etc.



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