AFP Polyclonal Antibody

Verified Samples in WB:Hep G2,Mouse placenta,Rat placenta,Mouse Fetal liver,Rat Fetal liver,Mouse liver,Mouse kidney,Rat liver,Rat kidney
Verified Samples in IHC:Mouse liver,Human liver cancer,Human ovarian cancer, MCF-7, MCF-7,Human liver cancer

WB:1:500-1:1000, IHC 1:200-1:500, IF 1:100-1:200

Polyclonal

IgG

Recombinant Mouse Afp protein expressed by E.coli

AFP

Afp; AFPD; Alpha fetoglobulin; Alpha fetoprotein precursor; Alpha-1-fetoprotein; FETA; Hereditary persistence of alpha fetoprotein; HPAFP抗体

67 kDa

73 kDa

Secreted

1.1mg/mL

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

PBS with 0.05% Proclin300 and 50% glycerol, pH7.4.

Antigen Affinity Purification

Cancer; Cardiovascular; Developmental Biology

Unconjugated

This gene encodes alpha-fetoprotein, a major plasma protein produced by the yolk sac and the liver during fetal life. Alpha-fetoprotein expression in adults is often associated with hepatoma or teratoma. However, hereditary persistance of alpha-fetoprotein may also be found in individuals with no obvious pathology. The protein is thought to be the fetal counterpart of serum albumin, and the alpha-fetoprotein and albumin genes are present in tandem in the same transcriptional orientation on chromosome 4. Alpha-fetoprotein is found in monomeric as well as dimeric and trimeric forms, and binds copper, nickel, fatty acids and bilirubin. The level of alpha-fetoprotein in amniotic fluid is used to measure renal loss of protein to screen for spina bifida and anencephaly.