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APC Anti-Human MPO Antibody[ABT-101007]

Uniprot : P05164

货号: E-AB-F1364E
应用: ICFCM
Isotype: Mouse IgG1, κ
宿主: Mouse

Applications:

ICFCM

说明书

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规格:

20Tests
100Tests
100Tests×2

价格: ￥1680

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Antigen Details

Alternate Names	Myeloperoxidase
Swissprot	P05164
Gene ID	4353
References	1. Goedken M, et al. 2007. J. Biol. Chem. 282:27994 2. Nauseef WM, et al. 1988. Euro. J. Haemat. 40:97 3. Kelebanoff SJ, et al.1999. Proc. Assoc. Am. Phys. 111:383

Product Details

Form	Liquid
Clone No.	ABT-101007 (See Other Available Formats)
Host	Mouse
Isotype	Mouse IgG1, κ
Isotype Control	APC Mouse IgG1, κ Isotype Control[MOPC-21] [Product E-AB-F09792E]
Reactivity	Human
Application	ICFCM (See the Application Description)
Storage Buffer	Phosphate buffered solution, pH 7.2, containing 0.09% sodium azide and 1% BSA.
Recommended Use	Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. The amount of the reagent is suggested to be used 5 μL of antibody per test (million cells in 100 μL staining volume or per 100 μL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Shipping	Biological ice pack at 4℃
Stability & Storage	Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Conjugation	APC
	APC is designed to be excited by the Red (627-640 nm) laser and detected using an optical filter centered near 660 nm (e.g., a 660/20 nm bandpass filter).

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Background

Myeloperoxidase (MPO) is a heterotetrameric protein consisting of two 60 kD heavy units and two 12 kD light units. A lysosomal enzyme, MPO is able to catalyze the production of hypochlorous acid, a potent microbicidal agent, from hydrogen peroxide and chloride anion during the neutrophil respiratory burst. MPO is a major enzyme involved in the inflammatory responses of polymorphonuclear leucocytes. MPO is localized to the azurophilic granules of mature granulocytes and monocytes and is also expressed in some acute myeloid leukemia cells.