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APC Anti-Mouse IL-17A Antibody[TC11-18H10.1]

Price: ¥1200 ¥720 ¥1920

Size:
100Tests 50Tests 100Tests×2
  • 应用性: ICFCM
  • 亚型: Rat IgG1, κ
  • 宿主: Rat
Background
IL-17, also known as CTLA-8, is a T cell-expressed pleiotropic cytokine that exhibits a high degree of homology to a protein encoded by the ORF13 gene of herpes virus Saimiri. IL-17 is produced by Th cells (Th17) that are distinct from the traditional Th1- and Th2-cell subsets. IL-23 plays an important role in triggering IL-17 production. Both recombinant and natural IL-17 have been shown to exist as disulfide linked homodimers. IL-17 exhibits multiple biological activities on a variety of cells including: the induction of IL-6 and IL-8 production in fibroblasts, activation of NF-κB, and costimulation of T cell proliferation. IL-17 is an essential inflammatory mediator in the development of autoimmune diseases. Neutralization of IL-17 with monoclonal antibody is able to ameliorate the disease course.
Alternate Names
Interleukin-17A;IL-17;IL-17A;Cytotoxic T-lymphocyte-associated antigen 8;CTLA-8;CTLA8;
Swissprot
Gene ID
Clone No
Host
Rat
Reactivity
Mouse
Application
Isotype
Rat IgG1, κ
Isotype Control
Conjugation
APC
Conjugation Information
APC is designed to be excited by the Red (627-640 nm) laser and detected using an optical filter centered near 660 nm (e.g., a 660/20 nm bandpass filter).
Spectrum
Storage Buffer
Phosphate buffered solution, pH 7.2, containing 0.09% sodium azide and 1% BSA.
Storage
This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.
Expiration date
12个月
Shipping
冰袋
HEK293T cells transiently transfected with pcDNA3.1 plasmid encoding Mouse IL-17A gene are stained with APC Anti-Mouse IL-17A Antibody (filled gray histogram) or APC Rat IgG1, κ lsotype Control (empty black histogram).
E-AB-F1199B Biotin Anti-Mouse IL-17A Antibody[TC11-18H10.1] 100μg , 25μg
E-AB-F1199C FITC Anti-Mouse IL-17A Antibody[TC11-18H10.1] 100Tests , 50Tests , 100Tests×2
E-AB-F1199D PE Anti-Mouse IL-17A Antibody[TC11-18H10.1] 100Tests , 50Tests , 100Tests×2
E-AB-F1199M Elab Fluor® 647 Anti-Mouse IL-17A Antibody[TC11-18H10.1] 100Tests , 50Tests , 100Tests×2
E-AB-F1199UC FITC Anti-Mouse IL-17A Antibody[TC11-18H10.1] 100μg , 25μg
E-AB-F1199UD PE Anti-Mouse IL-17A Antibody[TC11-18H10.1] 100μg , 25μg
E-AB-F1199UE APC Anti-Mouse IL-17A Antibody[TC11-18H10.1] 100μg , 25μg
E-AB-F1199UM Elab Fluor® 647 Anti-Mouse IL-17A Antibody[TC11-18H10.1] 100μg , 25μg


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