APLNR Polyclonal Antibody

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- 宿主: Rabbit
- 反应性: Human;Mouse;Rat
- 应用性: IHC
Verified Samples |
Verified Samples in IHC: Human liver cancer, Human thyroid cancer |
Dilution | IHC 1:50-1:200 |
Clonality | Polyclonal |
Isotype | IgG |
Immunogen | Recombinant protein of human APLNR |
Abbre | APLNR |
Synonyms | AGTR L1, AGTRL 1, AGTRL1, APJ, APJ (apelin) receptor, APJ receptor, APJR, APLNR, Angiotensin II receptor like 1, Angiotensin receptor like 1, Angiotensin receptor-like 1, Apelin receptor, B78, FLJ90771, G protein coupled receptor APJ, G-protein coupled receptor APJ |
Swissprot | |
Cellular Localization | Cell membrane. |
Concentration | 0.4 mg/mL |
Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
Buffer | PBS with 0.05% sodium azide and 50% glycerol, pH 7.4. |
Purification Method | Affinity purification |
Research Areas | Cancer, Cardiovascular, Metabolism, Neuroscience, Signal Transduction |
Conjugation | Unconjugated |
Background | This gene encodes a member of the G protein-coupled receptor gene family. The encoded protein is related to the angiotensin receptor, but is actually an apelin receptor that inhibits adenylate cyclase activity and plays a counter-regulatory role against the pressure action of angiotensin II by exerting hypertensive effect. It functions in the cardiovascular and central nervous systems, in glucose metabolism, in embryonic and tumor angiogenesis and as a human immunodeficiency virus (HIV-1) coreceptor. Two transcript variants resulting from alternative splicing have been identified. |
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