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BCL2 Monoclonal Antibody

Price: ¥2310 ¥1420 ¥580

Size:
120μL 60μL 20μL
  • 宿主: Mouse
  • 反应性: Human;Mouse;Rat
  • 应用性: WB;IHC-p
Verified Samples
Verified Samples in WB:Hela
Verified Samples in IHC:Human tonsil
Dilution
WB 1:1000-2000, IHC 1:50-1:200
Clonality
Monoclonal
Isotype
IgG
Immunogen
Synthetic Peptide
Abbre
Bcl-2
Synonyms
Apoptosis regulator Bcl 2;Apoptosis regulator Bcl-2;Apoptosis regulator Bcl2;AW986256;B cell CLL/lymphoma 2;B cell leukemia/lymphoma 2;Bcl-2;Bcl2;BCL2;C430015F12Rik;D630044D05Rik;D830018M01Rik;Leukemia/lymphoma;B-cell;2;Oncogene B-cell leukemia 2;PPP1R50;Protein phosphatase 1;regulatory subunit 50抗体
Swissprot
Calculated MW
26kDa
Observed MW
26kDa
Cellular Localization
Mitochondrion outer membrane. Nucleus membrane. Endoplasmic reticulum membrane.
Tissue Specificity
Expressed in a variety of tissues.
Concentration
1 mg/mL
Storage
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Buffer
PBS with 0.02% sodium azide and 50% glycerol pH 7.4.
Purification Method
Protein A purification
Research Areas
Cancer; Cell Biology; Metabolism; Signal Transduction
Clone No.
Clone:1B3
Conjugation
Unconjugated
Background
Suppresses apoptosis in a variety of cell systems including factor-dependent lymphohematopoietic and neural cells. Regulates cell death by controlling the mitochondrial membrane permeability. Appears to function in a feedback loop system with caspases. Inhibits caspase activity either by preventing the release of cytochrome c from the mitochondria and/or by binding to the apoptosis-activating factor (APAF-1).
Western Blot analysis of Hela cells using BCL2 Monoclonal Antibody at dilution of 1:1000.
Immunohistochemistry of paraffin-embedded Human tonsil tissue using BCL2 Monoclonal Antibody at dilution of 1:200.


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