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BSG Polyclonal Antibody

Price: ¥2365 ¥1640 ¥1010 ¥420

Size:
200μL 120μL 60μL 20μL
  • 宿主: Rabbit
  • 反应性: Mouse;Rat
  • 应用性: WB;IHC
Verified Samples
Verified Samples in WB:Mouse heart,Rat liver,Rat heart,Rat kidney,Rat brain
Verified Samples in IHC:Rat liver,Rat stomach
Dilution
WB 1:1000-1:2000 , IHC 1:100-1:300
Clonality
Polyclonal
Isotype
IgG
Immunogen
Recombinant Rat Basigin protein
Abbre
BSG
Synonyms
5A11 antigen;5F7;BASI;Basigin (Ok blood group);Basigin;Blood brain barrier HT7 antigen;Bsg;CD 147;CD147;CD147 antigen;Collagenase stimulatory factor;EMMPRIN;Extracellular matrix metalloproteinase inducer;Leukocyte activation antigen M6;M 6;M6;M6 leukocyte activation antigen;Neurothelin;OK;OK blood group;OK blood group antigen;TCSF;Tumor cell derived collagenase stimulatory factor;Tumor cell-derived collagenase stimulatory factor抗体
Swissprot
Calculated MW
30kDa,40-60kDa
Observed MW
30kDa,40-60kDa
Cellular Localization
Cell membrane
Concentration
1 mg/mL
Storage
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Buffer
PBS with 0.05% Proclin300 and 50% glycerol, pH7.4.
Purification Method
Antigen Affinity Purification
Research Areas
Cancer; Cardiovascular; Metabolism; Immunology; Neuroscience
Conjugation
Unconjugated
Background
BSG,also named as 5F7,Basigin,EMMPRIN,TCSF and CD147,plays pivotal roles in spermatogenesis,embryo implantation,neural network formation and tumor progression. It stimulates adjacent fibroblasts to produce matrix metalloproteinases (MMPS).CD147 may target monocarboxylate transporters SLC16A1,SLC16A3 and SLC16A8 to plasma membranes of retinal pigment epithelium and neural retina. It seems to be a receptor for oligomannosidic glycans. CD147 is a receptor of CypA,inducing matrix metalloproteinase expression and mediating the degradation of the extracellular matrix,plays an important role in tumorigenesis and invasion in oral cancer. It has been considered as an objective and effective marker to predict invasion and prognosis in various cancers.
Western Blot analysis of Rat liver, Rat heart,Rat kidney and Rat brain using BSG Polyclonal Antibody at dilution of 1:2000
Western Blot analysis of Mouse heart using BSG Polyclonal Antibody at dilution of 1:1000
Immunohistochemistry of paraffin-embedded Rat liver using BSG Polyclonal Antibody at dilution of 1:200
Immunohistochemistry of paraffin-embedded Rat stomach using BSG Polyclonal Antibody at dilution of 1:200


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