Cathepsin B Polyclonal Antibody

Verified Samples in IHC:Human lung cancer,Human liver

IHC 1:50-1:100

Polyclonal

IgG

Recombinant protein of human CTSB

CTSB

Amyloid precursor protein secretase;APP secretase;APPS;CATB;Cathepsin B heavy chain;Cathepsin B1;CathepsinB;CPSB;CTSB;cysteine protease;OTTHUMP00000116009;OTTHUMP00000229510;OTTHUMP00000229511;OTTHUMP00000229512;OTTHUMP00000229514;OTTHUMP00000229515;OTTHUMP00000229516;Preprocathepsin B抗体

Lysosome. Melanosome. Identified by mass spectrometry in melanosome fractions from stage I to stage IV.

0.3 mg/mL

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Affinity purification

Cancer; Neuroscience; Signal Transduction

Unconjugated

The protein encoded by this gene is a lysosomal cysteine proteinase composed of a dimer of disulfide-linked heavy and light chains, both produced from a single protein precursor. It is also known as amyloid precursor protein secretase and is involved in the proteolytic processing of amyloid precursor protein (APP). Incomplete proteolytic processing of APP has been suggested to be a causative factor in Alzheimer disease, the most common cause of dementia. Overexpression of the encoded protein, which is a member of the peptidase C1 family, has been associated with esophageal adenocarcinoma and other tumors. At least five transcript variants encoding the same protein have been found for this gene.