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CD40 Polyclonal Antibody

Price: ¥2365 ¥1640 ¥1010 ¥420

Size:
200μL 120μL 60μL 20μL
  • 宿主: Rabbit
  • 反应性: Human;Mouse
  • 应用性: IHC
Verified Samples
Verified Samples in IHC:Human liver cancer,Human gastric cancer
Dilution
IHC 1:100-1:300
Clonality
Polyclonal
Isotype
IgG
Immunogen
Synthetic peptide of human CD40
Abbre
CD40
Synonyms
AI326936;B cell associated molecule CD40;B cell surface antigen CD40;B cell-associated molecule;B-cell surface antigen CD40;Bp50;CD 40;CD40;CD40 antigen (TNF receptor superfamily member 5);CD40 antigen;CD40 molecule;CD40 molecule;TNF receptor superfamily member 5;CD40 protein;CD40 type II isoform;CD40L receptor;CDw40;GP39;HIGM1;IGM;IMD3;MGC9013;Nerve growth factor receptor related B lymphocyte activation molecule;OTTHUMP00000031699;OTTHUMP00000031700;p50;T-BAM;TBAM;TNF receptor superfamily member 5;TNFRSF5;TNR5;TRAP;Tumor necrosis factor receptor superfamily;member 5;Tumor necrosis factor receptor superfamily member 5;Tumor necrosis factor receptor superfamily member 5 precursor;Tumor necrosis factor receptor superfamily;member 5;isoform CRA_a抗体
Swissprot
Cellular Localization
Secreted and Cell membrane.
Concentration
1.3 mg/mL
Storage
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Purification Method
Affinity purification
Research Areas
Cancer; Cardiovascular; Immunology; Stem cells
Conjugation
Unconjugated
Background
The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor has been found to be essential in mediating a broad variety of immune and inflammatory responses including T cell-dependent immunoglobulin class switching, memory B cell development, and germinal center formation. AT-hook transcription factor AKNA is reported to coordinately regulate the expression of this receptor and its ligand, whicHuman, Mouseay be important for homotypic cell interactions. Adaptor protein TNFR2 interacts with this receptor and serves as a mediator of the signal transduction. The interaction of this receptor and its ligand is found to be necessary for amyloid-beta-induced microglial activation, and thus is thought to be an early event in Alzheimer disease pathogenesis.
Immunohistochemistry of paraffin-embedded Human liver cancer tissue using CD40 Polyclonal Antibody at dilution 1:70
Immunohistochemistry of paraffin-embedded Human gastric cancer tissue using CD40 Polyclonal Antibody at dilution 1:70


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