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CD59 Polyclonal Antibody

CD59 Polyclonal Antibody
  • CD59 Polyclonal Antibody
  • CD59 Polyclonal Antibody
  • CD59 Polyclonal Antibody

Price: ¥2100.00 ¥800.00

Size:
100 μL 25 μL
  • 宿主: Rabbit
  • 反应性: Human
  • 应用性: WB;IHC
Verified Samples
Verified Samples in WB: Human HUVEC, Human U87-MG, Human Hela
Verified Samples in IHC: Human ovary
Dilution
WB 1:500-1:1000, IHC 1:250-1:500
Clonality
Polyclonal
Isotype
IgG
Immunogen
Recombinant Human CD59 protein expressed by E.coli
Abbre
CD59
Synonyms
16.3A5, 1F5, 1F5 antigen, 20 kDa homologous restriction factor, CD 59, CD59, CD59 antigen, CD59 antigen complement regulatory protein , CD59 antigen p18 20, CD59 antigen p18-20 (antigen identified by monoclonal antibodies 16.3A5, CD_antigen=CD59, EJ16, EJ30, EL32 and
Swissprot
Calculated MW
14 kDa
Observed MW
14-17 kDa
Concentration
1 mg/mL
Storage
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Buffer
PBS with 0.05% proclin 300, 1% protective protein and 50% glycerol,pH7.4
Purification Method
Antigen Affinity Purification
Research Areas
Cancer, Cardiovascular, Immunology, Signal Transduction, Stem Cells
Conjugation
Unconjugated
Background
This gene encodes a cell surface glycoprotein that regulates complement-mediated cell lysis, and it is involved in lymphocyte signal transduction. This protein is a potent inhibitor of the complement membrane attack complex, whereby it binds complement C8 and/or C9 during the assembly of this complex, thereby inhibiting the incorporation of multiple copies of C9 into the complex, which is necessary for osmolytic pore formation. This protein also plays a role in signal transduction pathways in the activation of T cells. Mutations in this gene cause CD59 deficiency, a disease resulting in hemolytic anemia and thrombosis, and which causes cerebral infarction.
Western blot with CD59 Polyclonal antibody at dilution of 1:1000.lane 1:HUVEC whole cell lysate, lane 2:U87-MG whole cell lysate, lane 3:Hela whole cell lysate
Immunohistochemistry of paraffin-embedded Human ovary using CD59 Polyclonal Antibody at dilution of 1:500


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