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CD86 Polyclonal Antibody

Price: ¥2365 ¥1640 ¥1010 ¥420

Size:
200μL 120μL 60μL 20μL
  • 宿主: Rabbit
  • 反应性: Human
  • 应用性: WB;IHC
Verified Samples
Verified Samples in WB:Human lymph gland,Jurkat
Verified Samples in IHC:Human gastric cancer
Dilution
WB 1:500-1:2000, IHC 1:25-1:100
Clonality
Polyclonal
Isotype
IgG
Immunogen
Fusion protein of human CD86
Abbre
CD86
Synonyms
Activation B7-2 antigen 3;Activation B7-2 antigen;B-lymphocyte activation antigen B7-2 2;B-lymphocyte activation antigen B7-2;B7 2;B7;B7-2;B7.2;B70;B72 antigen;BU63;CD28 antigen ligand 2 2;CD28 antigen ligand 2;Cd28l2;CD28LG2;CD86;CD86 antigen;CD86 antigen;CD86 molecule;CD86;CLS1;CTLA-4 counter-receptor B7.2 2;3;CTLA-4 counter-receptor B7.2;Early T-cell costimulatory molecule 1;ETC-1;FUN 1;FUN-1;LAB72;Ly-58;Ly58;MB7;MB7-2;Membrane glycoprotein;MGC34413;T-lymphocyte activation antigen CD86;TS/A-2抗体
Swissprot
Calculated MW
38 kDa
Observed MW
Refer to figures
Cellular Localization
Membrane.
Concentration
0.5 mg/mL
Storage
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Buffer
PBS with 0.05% NaN3 and 40% Glycerol,pH7.4
Purification Method
Antigen affinity purification
Research Areas
Cancer; Immunology; Microbiology; Stem Cells
Conjugation
Unconjugated
Background
This gene encodes a type I membrane protein that is a member of the immunoglobulin superfamily. This protein is expressed by antigen-presenting cells, and it is the ligand for two proteins at the cell surface of T cells, CD28 antigen and cytotoxic T-lymphocyte-associated protein 4. Binding of this protein with CD28 antigen is a costimulatory signal for activation of the T-cell. Binding of this protein with cytotoxic T-lymphocyte-associated protein 4 negatively regulates T-cell activation and diminishes the immune response. Alternative splicing results in several transcript variants encoding different isoforms.
Western blot analysis of Human lymph gland tissue and Jurkat cell lysates using CD86 Polyclonal Antibody at dilution of 1:450
Immunohistochemistry of paraffin-embedded Human gastric cancer tissue using CD86 Polyclonal Antibody at dilution of 1:30(×200)


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