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CDH12 Polyclonal Antibody

Price: ¥2365 ¥1640 ¥1010 ¥420

Size:
200μL 120μL 60μL 20μL
  • 宿主: Rabbit
  • 反应性: Human; Mouse
  • 应用性: IHC
Verified Samples
Verified Samples in IHC:Human brain,Human ovarian cancer
Dilution
IHC 1:50-1:100
Clonality
Polyclonal
Isotype
IgG
Immunogen
Synthetic peptide of human CDH12
Abbre
CDH12
Synonyms
Br cadherin;BR-cadherin;Brain cadherin;CAD12_HUMAN;cadherin 12 (N cadherin 2);Cadherin 12;Cadherin 12 precursor;Cadherin 12 type 2 (N cadherin 2);Cadherin 12 type 2;Cadherin neural type 2;Cadherin-12;CDH12;CDHB;FLJ34857;N cadherin 2;N-cadherin 2;Neural type cadherin 2;Neuronal cadherin 2抗体
Swissprot
Cellular Localization
Membrane
Concentration
1.74 mg/mL
Storage
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Buffer
PBS with 0.05% NaN3 and 40% Glycerol,pH7.4
Purification Method
Antigen affinity purification
Research Areas
Signal Transduction
Conjugation
Unconjugated
Background
This gene encodes a type II classical cadherin of the cadherin superfamily. Alternative splicing of this gene results in multiple transcript variants. At least one of these variants encodes a preproprotein that is proteolytically processed to generate the mature cadherin protein. These integral membrane proteins mediate calcium-dependent cell-cell adhesion and are composed of a large N-terminal extracellular domain, a single membrane-spanning domain, and a small, highly conserved C-terminal cytoplasmic domain. Type II (atypical) cadherins are defined based on their lack of a histidine-alanine-valine (HAV) cell adhesion recognition sequence specific to type I cadherins. This particular cadherin appears to be expressed specifically in the brain and its temporal pattern of expression would be consistent with a role during a critical period of neuronal development, perhaps specifically during synaptogenesis.
Immunohistochemistry of paraffin-embedded Human brain tissue using CDH12 Polyclonal Antibody at dilution of 1:60(×200)
Immunohistochemistry of paraffin-embedded Human ovarian cancer tissue using CDH12 Polyclonal Antibody at dilution of 1:60(×200)


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