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CDH5 Polyclonal Antibody

Price: ¥2365 ¥1640 ¥1010 ¥420

Size:
200μL 120μL 60μL 20μL
  • 宿主: Rabbit
  • 反应性: Human
  • 应用性: IHC
Verified Samples
Verified Samples in IHC:Human thyroid cancer,Human ovarian cancer
Dilution
IHC 1:50-1:200
Clonality
Polyclonal
Isotype
IgG
Immunogen
Synthetic peptide of human CDH5
Abbre
CDH5
Synonyms
7B 4;7B4;7B4 antigen;CADH5;Cadherin 5;Cadherin 5 type 2;Cadherin 5;type 2 (vascular endothelium);Cadherin 5;type 2;VE cadherin (vascular epithelium);cadherin;vascular endothelial;cadherin;vascular endothelial;1;Cadherin-5;Cadherin5;CD 144;CD144;CD144 antigen;CDH 5;CDH5;CDH5 protein;Endothelial specific cadherin;FLJ17376;OTTHUMP00000174777;Vascular endothelial cadherin;Vascular epithelium cadherin;VE Cad;VE-cadherin;VEC抗体
Swissprot
Cellular Localization
Cell junction. Cell membrane. Found at cell-cell boundaries and probably at cell-matrix boundaries.
Concentration
0.6 mg/mL
Storage
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Buffer
PBS with 0.05% NaN3 and 40% Glycerol,pH7.4
Purification Method
Antigen affinity purification
Research Areas
Cancer; Cardiovascular; Signal Transduction
Conjugation
Unconjugated
Background
This gene is a classical cadherin from the cadherin superfamily and is located in a six-cadherin cluster in a region on the long arm of chromosome 16 that is involved in loss of heterozygosity events in breast and prostate cancer. The encoded protein is a calcium-dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Functioning as a classic cadherin by imparting to cells the ability to adhere in a homophilic manner, the protein may play an important role in endothelial cell biology through control of the cohesion and organization of the intercellular junctions. An alternative splice variant has been described but its full length sequence has not been determined.
Immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using CDH5 Polyclonal Antibody at dilution of 1:30(×200)
Immunohistochemistry of paraffin-embedded Human ovarian cancer tissue using CDH5 Polyclonal Antibody at dilution of 1:30(×200)


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