Chromogranin A Polyclonal Antibody

Verified Samples in WB:PC-3
Verified Samples in IHC:Human duodenum,Mouse small intestine,Mouse pancreas

WB 1:500-1:1000 , IHC 1:100-1:300

Polyclonal

IgG

Recombinant Mouse Chromogranin-A protein

Chromogranin A

beta Granin;betagranin (N-terminal fragment of chromogranin A);catestatin;CgA;CHG A;Chga;chromofungin;Chromogranin A;Chromogranin A parathyroid secretory protein 1;Chromogranin A precursor;ChromograninA;CMGA;ER-37;Pancreastatin;Parastatin;Parathyroid secretory protein 1;Pituitary secretory protein I;Secretory protein I;SP I;SP-I;SP1;SPI;Vasostatin;Vasostatin I;Vasostatin II抗体

51 kDa

51 kDa

Cytoplasmic vesicle, Membrane, Secreted

1 mg/mL

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

PBS with 0.05% Proclin300 and 50% glycerol, pH7.4.

Antigen Affinity Purification

Cancer; Neuroscience; Signal Transduction; Tags and Cell Markers

Unconjugated

Chromogranin A is a member of the granin family of neuroendocrine secretory proteins. It is located in secretory vesicles of neurons and endocrine cells. Chromogranin A is the precursor to several functional peptides including vasostatin,pancreastatin,catestatin and parastatin. These peptides negatively modulate the neuroendocrine function of the releasing cell (autocrine) or nearby cells (paracrine). CgA is one of the most used tumor markers in NET's (neuroendocrine tumors) ,and elevated CgA concentrations have been demonstrated in serum or plasma of patients with different types of these tumors.