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Elab Fluor® Violet 450 Anti-Human CD196/CCR6 Antibody[G034E3]

Price: ¥3420 ¥1440 ¥5100

Size:
100Tests 20Tests 100Tests×2
  • 应用性: FCM
  • 亚型: Mouse IgG2b, κ
  • 宿主: Mouse
Background
CCR6, also known as CD196/CCR6, is a chemokine receptor that is expressed on immature dendritic cells, B lymphocytes, and memory T cells. CCR6 binds CCL20, although members of the β defensin family also bind CCR6 with a lower affinity. CCR6 positive cells, and its ligand CCL20, have been detected in numerous organs, especially the secondary lymphoid organ. CCL20 is selectively made by the follicle-associated epithelium (FAE) overlying Peyers Patches (PPs) and isolated lymphoid follicles (ILFs). CCL20 contributes to the recruitment of CCR6-expressing B cells to these structures. In humans, CCR6 can function to mediate arrest of T cells on dermal endothelial cells and is highly expressed on T cells resident in both normal and psoriatic skin. CCR6 and/or CCL20 have been implicated in the pathogenesis of rheumatoid arthritis and inflammatory bowel disease. Human T cells that are able to produce IL-17 express CCR6. It suggests that CCL20 and CCR6 have a role in inflammatory diseases by recruiting Th17 cells to target tissues.
Alternate Names
CKRL3; CMKBR6; GPR29; STRL22;GPRCY4;
Swissprot
Gene ID
Clone No
Host
Mouse
Reactivity
Human
Application
Isotype
Mouse IgG2b, κ
Isotype Control
Conjugation
Elab Fluor®Violet 450
Conjugation Information
Elab Fluor® Violet 450 is designed to be excited by the violet laser (405 nm) and detected using an optical filter centered near 450 nm (e.g., a 450/45 nm bandpass filter).
Spectrum
Storage Buffer
Phosphate buffered solution, pH 7.2, containing 0.09% sodium azide and 1% BSA.
Storage
This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.
Expiration date
12个月
Shipping
冰袋
Human peripheral blood lymphocytes are stained with APC Anti-Human CD19 Antibody and Elab Fluor® Violet 450 Anti-Human CD196/CCR6 Antibody (Left). Lymphocytes are stained with APC Anti-Human CD19 Antibody and Elab Fluor® Violet 450 Mouse IgG2b, κ Isotype Control (Right).
E-AB-F1158C FITC Anti-Human CD196/CCR6 Antibody[G034E3] 100Tests , 20Tests , 100Tests×2
E-AB-F1158D PE Anti-Human CD196/CCR6 Antibody[G034E3] 100Tests , 20Tests , 100Tests×2
E-AB-F1158E APC Anti-Human CD196/CCR6 Antibody[G034E3] 100Tests , 20Tests , 100Tests×2
E-AB-F1158H PE/Cyanine7 Anti-Human CD196/CCR6 Antibody[G034E3] 100Tests , 20Tests , 100Tests×2
E-AB-F1158M Elab Fluor® 647 Anti-Human CD196/CCR6 Antibody[G034E3] 100Tests , 20Tests , 100Tests×2


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