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Elab Fluor^® 647 Anti-Mouse CD163 Antibody[S15049F]

Uniprot : Q2VLH6

货号: E-AB-F1295UM
应用: FCM
Isotype: Rat IgG2a, κ
宿主: Rat

Applications:

说明书

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规格:

25μg
100μg

价格: ￥1560

数量:

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Antigen Details

Alternate Names	M130, MM130, SCARI1
Swissprot	Q2VLH6
Gene ID	93671

Product Details

Form	Liquid
Clone No.	S15049F (See Other Available Formats)
Host	Rat
Isotype	Rat IgG2a, κ
Isotype Control	Elab Fluor^® 647 Rat IgG2a, κ Isotype Control[2A3] [Product E-AB-F09833M]
Reactivity	Mouse
Application	FCM (See the Application Description)
Storage Buffer	Phosphate buffered solution, pH 7.2, containing 0.09% sodium azide and 1% BSA.
Recommended Use	Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/10⁶ cells in 100 μL volume].
Shipping	Biological ice pack at 4℃
Stability & Storage	Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Conjugation	Elab Fluor^® 647
	Elab Fluor^® 647 is designed to be excited by the Red laser (627-640 nm) and detected using an optical filter centered near 670 nm (e.g., a 660/20 nm bandpass filter).

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Background

CD163 is a member of the group B scavenger receptor cysteine-rich superfamily, also known as GHI/61, M130, RM3/1, p155, hemoglobin-haptoglobin complex receptor, or macrophage-associated antigen. It is a 134 kD (non-reduced)/155 kD (reduced) glycoprotein primarily expressed on macrophages, Kupffer cells, monocytes, a subset of dendritic cells, and a subset of hematopoietic stem/progenitor cells. CD163 binds to haptoglobin-hemoglobin complex and TWEAK, and plays a role in clearing hemoglobin and regulating cytokine production by macrophages. Membrane CD163 can be cleaved by metalloproteinases (MMP), resulting in a soluble form. Elevated serum level of sCD163 has been implicated in many kinds of inflammatory diseases.

Protocols & Troubleshootings

Related Protocols	细胞内细胞因子染色步骤
Troubleshooting	流式实验常见问题及解决方案

Alternative Formats

Cat.No.	Product Name	Sizes
E-AB-F1295E	APC Anti-Mouse CD163 Antibody[S15049F]	50Tests, 100Tests, 100Tests×2
E-AB-F1295M	Elab Fluor^® 647 Anti-Mouse CD163 Antibody[S15049F]	50Tests, 100Tests, 100Tests×2
E-AB-F1295UE	APC Anti-Mouse CD163 Antibody[S15049F]	25μg, 100μg