请输入货号/产品关键词 !
插入特殊字符:
  • α
  • β
  • γ
  • δ
  • ε
  • ζ
  • η
  • θ
  • κ
  • μ
  • ω
  • σ
  • τ
  • λ
  • ⅩⅢ
  • ⅩⅢ
  • ⅩⅣ
  • ⅩⅤ
  • ⅩⅦ
  • ⅩⅧ
  • 收起 ↑
热门搜索: 最新活动 文献引用 新品速递 一步法ELISA 流式抗体 铜死亡 Annexin V凋亡检测 TUNEL凋亡检测 未包被ELISA 铁死亡 双硫死亡

Elab Fluor® 488 Anti-Human CD8a Antibody[HIT8a]

Price: ¥2736 ¥960 ¥4104

Size:
100Tests 20Tests 100Tests×2
  • 应用性: FCM
  • 亚型: Mouse IgG1, κ
  • 宿主: Mouse
Background
CD8a is a 32-34 kD type I glycoprotein. It forms a homodimer (CD8a/a) or heterodimer (CD8a/b) with CD8b. CD8, also known as T8 and Leu2, is a member of the immunoglobulin superfamily found on the majority of thymocytes, a subset of peripheral blood T cells, and NK cells (which express almost exclusively CD8a homodimers). CD8 acts as a co-receptor with MHC class I-restricted T cell receptors in antigen recognition and T cell activation and has been shown to play a role in thymic differentiation. Two domains in CD8a are important for function: the extracellular IgSF domain binds the α3 domain of MHC class I and the cytoplasmic CXCP motif binds the tyrosine kinase p56 Lck.
Alternate Names
T-cell surface glycoprotein CD8 alpha chain;CD8A;T8;Leu2;MAL;
Swissprot
Gene ID
Clone No
Host
Mouse
Reactivity
Human
Application
Isotype
Mouse IgG1, κ
Isotype Control
Conjugation
Elab Fluor®488
Conjugation Information
Elab Fluor® 488 is designed to be excited by the Blue laser (488 nm) and detected using an optical filter centered near 520 nm (e.g., a 525/40 nm bandpass filter).
Spectrum
Storage Buffer
Phosphate buffered solution, pH 7.2, containing 0.09% sodium azide and 1% BSA.
Storage
This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.
Expiration date
12个月
Shipping
冰袋
Human peripheral blood lymphocytes are stained with APC Anti-Human CD4 Antibody and Elab Fluor® 488 Anti-Human CD8a Antibody (Left). Lymphocytes are stained with APC Anti-Human CD4 Antibody and Elab Fluor® 488 Mouse IgG1, κ Isotype Control (Right).
E-AB-F1271C FITC Anti-Human CD8a Antibody[HIT8a] 100Tests , 20Tests , 100Tests×2
E-AB-F1271D PE Anti-Human CD8a Antibody[HIT8a] 100Tests , 20Tests , 100Tests×2

Q1:Are CD8 and CD8α the same index?

Yes they are. CD8 and CD8α are widely used markers for identifying cytotoxic T lymphocytes (CTLs). CD8 plays an important role in mediating the recognition and excution funtions of CTLs. CD8α is a subunit of CD8 complex, which means the α chain, and it is quite important in the formation of the complex. CD8α chain not only participates in the binding with MHC-I molecules, but also regulates the activity of CTLs by interacting with other signal molecules. Therefore, the expression level and functional status of CD8α can be used for evaluating the activation and effection of CTLs, as well as CD8.



微信客服 微信客服 在线留言 TOP