Factor IX/PTC/F9 Polyclonal Antibody(Capture/Detector)

Price:
- 宿主: Rabbit
- 反应性: Human
- 应用性: ELISA Capture/Detector
Verified Samples |
Verified Samples in ELISA: Recombinant Human Factor IX/PTC/F9 protein, Human serum, Human plasma |
Dilution | ELISA Capture 2-8 μg/mL, ELISA Detector 0.1-0.4 μg/mL |
Clonality | Polyclonal |
Isotype | Rabbit IgG |
Immunogen | Recombinant Human Factor IX/PTC/F9 protein expressed by Mammalian |
Abbre | Factor IX/PTC/F9 |
Synonyms | HEMB, P19, PTC, THPH8, Christmas Factor, |
Swissprot | |
Concentration | 1 mg/mL |
Storage | Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles. |
Buffer | Phosphate buffered solution, pH 7.2, containing 0.05% proclin 300. |
Purification Method | Antigen Affinity Purification |
Research Areas | Cardiovascular, Immunology |
Conjugation | Unconjugated |
Background | This gene encodes vitamin K-dependent coagulation factor IX that circulates in the blood as an inactive zymogen. This factor is converted to an active form by factor XIa, which excises the activation peptide and thus generates a heavy chain and a light chain held together by one or more disulfide bonds. The role of this activated factor IX in the blood coagulation cascade is to activate factor X to its active form through interactions with Ca+2 ions, membrane phospholipids, and factor VIII. Alterations of this gene, including point mutations, insertions and deletions, cause factor IX deficiency, which is a recessive X-linked disorder, also called hemophilia B or Christmas disease. |