FAS/CD95 Polyclonal Antibody

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- 宿主: Rabbit
- 反应性: Human
- 应用性: WB
Verified Samples |
Verified Samples in WB: HepG2, Hela |
Dilution | WB 1:250-1:500 |
Clonality | Polyclonal |
Isotype | IgG |
Immunogen | Recombinant Human FAS/CD95 protein expressed by E.coli |
Abbre | FAS/CD95 |
Synonyms | APT1, FASTM, TNFRSF6, ALPS1A, APO 1, Apo 1 antigen, CD95, FAS, FAS/CD95, FAS1, FASLG receptor |
Swissprot | |
Calculated MW | 37 kDa |
Observed MW | 38-45 kDa |
Concentration | 1 mg/mL |
Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
Buffer | PBS with 0.05% proclin 300, 1% protective protein and 50% glycerol,pH7.4 |
Purification Method | Antigen Affinity Purification |
Research Areas | Cancer, Cell Biology, Immunology |
Conjugation | Unconjugated |
Background | Fas (CD95/APO-1) is a transmembrane glycoprotein belonging to the tumor necrosis factor (TNF) receptor superfamily. It can mediate apoptosis by ligation with an agonistic anti-Fas antibody or Fas ligand. Stimulation of Fas results in the aggregation of its intracellular death domains,leading to the formation of the death-inducing signaling complex (DISC). FAS-mediated apoptosis may have a role in the induction of peripheral tolerance,in the antigen-stimulated suicide of mature T-cells,or both. The molecular mass of native Fas is 38 kDa,the high molecular weight form (40-55 kDa) of Fas is due to glycosylation. |
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Amentoflavone Induces Apoptosis and Reduces Expression of Anti-apoptotic and Metastasis-associated Proteins in Bladder Cancer
IF: 1.935Journal: ANTICANCER RESEARCH (2019)PMID:31262890Reactivity:HumanSample Type:Cell culture supernatant
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