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FITC Anti-Human CD11b Antibody[ICRF44]

Price: ¥1080 ¥360 ¥1872

Size:
100Tests 20Tests 100Tests×2
  • 应用性: FCM
  • 亚型: Mouse IgG1, κ
  • 宿主: Mouse
Background
CD11b is a 165-170 kD type I transmembrane glycoprotein also known as αMintegrin, Mac-1, CR3, and C3biR. CD11b non-covalently associates with integrin β2(CD18) and is expressed on granulocytes, monocytes/macrophages, dendritic cells, NK cells, and subsets of T and B cells. CD11b/CD18 is critical for the transendothelial migration of monocytes and neutrophils. It is also involved in granulocyte adhesion, phagocytosis, and neutrophil activation. CD11b/CD18 interacts with ICAM-1 (CD54), ICAM-2 (CD102), ICAM-4, CD14, CD23, heparin, iC3b, fibrinogen, and factor X.
Alternate Names
Integrin alpha-M;Itgam;CD11 antigen-like family member B;CR-3 alpha chain;Leukocyte adhesion receptor MO1;CD11b;
Swissprot
Gene ID
Clone No
Host
Mouse
Reactivity
Human
Application
Isotype
Mouse IgG1, κ
Isotype Control
Conjugation
FITC
Conjugation Information
FITC is designed to be excited by the Blue laser (488 nm) and detected using an optical filter centered near 530 nm (e.g., a 525/40 nm bandpass filter).
Spectrum
Storage Buffer
Phosphate buffered solution, pH 7.2, containing 0.09% sodium azide and 1% BSA.
Storage
This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.
Expiration date
12个月
Shipping
冰袋
Human peripheral blood granulocytes are stained with FITC Anti-Human CD11b Antibody (filled gray histogram) or Mouse IgG1 Isotype Control FITC (empty black histogram).
E-AB-F1146D PE Anti-Human CD11b Antibody[ICRF44] 100Tests , 20Tests , 100Tests×2
E-AB-F1146E APC Anti-Human CD11b Antibody[ICRF44] 100Tests , 20Tests , 100Tests×2
E-AB-F1146F PerCP Anti-Human CD11b Antibody[ICRF44] 100Tests , 20Tests , 100Tests×2
E-AB-F1146G PE/Cyanine5 Anti-Human CD11b Antibody[ICRF44] 100Tests , 20Tests , 100Tests×2
E-AB-F1146H PE/Cyanine7 Anti-Human CD11b Antibody[ICRF44] 100Tests , 20Tests , 100Tests×2
E-AB-F1146I PE/Cyanine5.5 Anti-Human CD11b Antibody[ICRF44] 100Tests , 20Tests , 100Tests×2
E-AB-F1146J PerCP/Cyanine5.5 Anti-Human CD11b Antibody[ICRF44] 100Tests , 20Tests , 100Tests×2
E-AB-F1146L Elab Fluor® 488 Anti-Human CD11b Antibody[ICRF44] 100Tests , 20Tests , 100Tests×2
E-AB-F1146M Elab Fluor® 647 Anti-Human CD11b Antibody[ICRF44] 100Tests , 20Tests , 100Tests×2
E-AB-F1146S Elab Fluor® Red 780 Anti-Human CD11b Antibody[ICRF44] 100Tests , 20Tests , 100Tests×2

Q1:What are the recommendations for flow cytometry of mouse macrophages to detect M1 and M2 type macrophages?

As a recommandation, F4/80 and CD11b are always used for identyfing macrophages of mouse, and CD86 and CD206 can be used for a further seperation for M1 abd M2 respectively. Specific indicators can be determined according to the literature and experimental requirements.



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