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FITC Anti-Human IL-17A Antibody[BL168]

Price: ¥2736 ¥900 ¥4104

Size:
100Tests 20Tests 100Tests×2
  • 应用性: ICFCM
  • 亚型: Mouse IgG1, κ
  • 宿主: Mouse
Background
IL-17A is the founding member of the IL-17 family, a group of six structurally related pro-inflammatory cytokines. IL-17A, secreted by activated CD4+ Th17 cell subpopulation, elicits multiple biological activities on a variety of cells including: the induction of IL-6, IL-8, G-CSF, and PGE2 production in epithelial, endothelial or fibroblasts; the enhancement of surface expression of ICAM-1 in fibroblasts; activation of NF-κB and costimulation of T cell proliferation. Recent studies demonstrated that, in mice, activated IL-17-secreting CD4+ helper T cells (Th17 cells) mediate an autoimmune arthritis that clinically and immunologically resembles rheumatoid arthritis (RA). Human IL-17A shows 63%, 63%, and 72% amino acid sequence identity to rat IL-17A, mouse IL-17A, and a protein encoded by the ORF13 gene of herpesvirus Saimiri (HVS), respectively.
Alternate Names
CTLA8; IL17;CTLA-8;IL 17A;
Swissprot
Gene ID
Clone No
Host
Mouse
Reactivity
Human
Application
Isotype
Mouse IgG1, κ
Isotype Control
Conjugation
FITC
Conjugation Information
FITC is designed to be excited by the Blue laser (488 nm) and detected using an optical filter centered near 530 nm (e.g., a 525/40 nm bandpass filter).
Spectrum
Storage Buffer
Phosphate buffered solution, pH 7.2, containing 0.09% sodium azide and 1% BSA.
Storage
This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.
Expiration date
12个月
Shipping
冰袋
HEK293T cells transiently transfected with pcDNA3.1 plasmid encoding Human IL-17A gene are stained with FITC Anti-Human IL-17A Antibody (filled gray histogram) or FITC Mouse IgG1, κ lsotype Control (empty black histogram).
E-AB-F1173D PE Anti-Human IL-17A Antibody[BL168] 100Tests , 20Tests , 100Tests×2
E-AB-F1173E APC Anti-Human IL-17A Antibody[BL168] 100Tests , 20Tests , 100Tests×2


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