IL-18/IL-1F4 Polyclonal Antibody(Capture/Detector)

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- 宿主: Rabbit
- 反应性: Human
- 应用性: ELISA Capture/Detector
Verified Samples |
Verified Samples in ELISA: Recombinant Human IL-18/IL-1F4 protein, Human serum, Human plasma |
Dilution | ELISA Capture 2-8 μg/mL, ELISA Detector 0.1-0.4 μg/mL |
Clonality | Polyclonal |
Isotype | Rabbit IgG |
Immunogen | Recombinant Human IL-18/IL-1F4 protein expressed by E.coli |
Abbre | IL-18/IL-1F4 |
Synonyms | IL18, IL-18, IGIF, IL1F4, Iboctadekin, Interferon gamma-inducing factor, InterLeukin-1 gamma (IL-1 gamma) |
Swissprot | |
Concentration | 1 mg/mL |
Storage | Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles. |
Buffer | Phosphate buffered solution, pH 7.2, containing 0.05% proclin 300. |
Purification Method | Antigen Affinity Purification |
Research Areas | Immunology, Cancer, Metabolism |
Conjugation | Unconjugated |
Background | Pro-inflammatory cytokine primarily involved in epithelial barrier repair,polarized T-helper 1 (Th1) cell and natural killer (NK) cell immune responses.Upon binding to Il18R1 and Il18RAP,forms a signaling ternary complex which activates NF-kappa-B,triggering synthesis of inflammatory mediators.Synergizes with Il12/interleukin-12 to induce IFNG synthesis from T-helper 1 (Th1) cells and natural killer (NK) cells.Involved in transduction of inflammation downstream of pyroptosis: its mature form is specifically released in the extracellular milieu by passing through the gasdermin-D (GSDMD) pore. |