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IL-22 Monoclonal Antibody(Detector)

IL-22 Monoclonal Antibody(Detector)
  • IL-22 Monoclonal Antibody(Detector)
  • IL-22 Monoclonal Antibody(Detector)

Price: ¥2100.00 ¥800.00 Inquire

Size:
100 μg 25 μg 1 mg
  • 宿主: Mouse
  • 反应性: Human
  • 应用性: ELISA Detector
Verified Samples
Verified Samples in ELISA: Recombinant Human IL-22 protein, Human serum, Human plasma
Dilution
ELISA Detector 0.1-0.4 μg/mL
Clonality
Monoclonal
Isotype
Mouse IgG1
Immunogen
Recombinant Human IL-22 protein expressed by Mammalian
Abbre
IL-22
Synonyms
Cytokine Zcyto18, IL-10-reLated T-ceLL-derived inducibLe factor, IL22, IL-22, IL-D110, IL-TIF, ILTIFIL-10-reLated T-ceLL-derived-inducibLe factor, IL-TIFMGC79382, interLeukin 22, interLeukin-22, MGC79384, TIFa, TIFIL-23, zcyto18
Swissprot
Concentration
1 mg/mL
Storage
Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles.
Buffer
Phosphate buffered solution, pH 7.2, containing 0.05% proclin 300.
Purification Method
Protein A/G Purification
Research Areas
Immunology
Clone No.
4E6
Conjugation
Unconjugated
Background
Interleukin-22 (Il-22),also known as Il-10-related T cell-derived inducible factor (Il-TIF) was initially identified as a gene induced by Il-9 in mouse T cells and mast cells. Mouse Il-22 cDNA encodes a 179 amino acid (aa) residue protein with a putative 33 aa signal peptide that is cleaved to generate a 147 aa mature protein that shares approximately 79% and 22% aa sequence identity with human Il-22 and Il-10,respectively. The mouse Il-22 gene is localized to chromosome 10. Although it exists as a single copy gene in many mouse strains,the Il-22 gene is duplicated in some mouse strains including C57B1/6,FVB and 129. The two mouse genes designated Il-TIF alpha and Il-TIF beta,share greater than 98% sequence homology in their coding region. Il-22 has been shown to activate STAT1 and STAT3 in several hepatoma cell lines and upregulate the production of acute phase proteins. Il-22 is produced by normal mouse T cells upon Con A activation. Mouse Il-22 expression is also induced in various organs upon lipopolysaccharide injection,suggesting that Il-22 may be involved in inflammatory responses. The functional Il-22 receptor complex consists of two receptor subunits,Il-22 R (previously an orphan receptor named CRF2-9) and Il-10 R beta (previously known as CRF2-4),belonging to the class II cytokine receptor family.
Sandwich ELISA-Recombinant Human IL-22 protein standard curve.Background subtracted standard curve using IL-22 antibody(AN001240P)(Capture),IL-22 antibody(AN001250P)(Detector) in sandwich ELISA.The reference range value for Recombinant Human IL-22 protein is 31.25-2000 pg/mL.
AN001240P IL-22 Monoclonal Antibody(Capture) 100 μg , 25 μg , 1 mg
PDMH100030 Recombinant Human IL-22 Protein 100 μg , 20 μg


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