MMP13 Polyclonal Antibody
Price:
- 宿主： Rabbit
- 反应性： Human;Mouse;Rat
- 应用性： WB
| Verified Samples |
Verified Samples in WB: Hela |
| Dilution | WB 1:500-1:2000 |
| Clonality | Polyclonal |
| Isotype | IgG |
| Immunogen | Recombinant protein of human MMP13 |
| Abbre | MMP13 |
| Synonyms | CLG 3, CLG3, Collagenase 3, Collagenase3, MANDP1, MMP 13, MMP-13, MMP13, Matrix Metalloproteinase 13, Matrix metallopeptidase 13 (collagenase 3), Matrix metalloproteinase-13, Mmp13 |
| Swissprot | |
| Calculated MW | 54 kDa |
| Cellular Localization | Secreted>extracellular space>extracellular matrix. |
| Concentration | 0.4 mg/mL |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Buffer | PBS with 0.05% sodium azide and 50% glycerol, pH 7.4. |
| Purification Method | Affinity purification |
| Research Areas | Cancer, Cell Biology, Cardiovascular, Signal Transduction |
| Conjugation | Unconjugated |
| Background | Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The protein encoded by this gene cleaves type II collagen more efficiently than types I and III. It may be involved in articular cartilage turnover and cartilage pathophysiology associated with osteoarthritis. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3. |
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Effects of 1,25-Dihydroxy vitamin D3 on TNF-α induced inflammation in human chondrocytes and SW1353 cells: a possible role for toll-like receptors
IF: 2.884Journal： MOLECULAR AND CELLULAR BIOCHEMISTRY (2019)PMID：31734843Reactivity：HumanSample Type：Cell culture supernatant
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