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Pancreatic polypeptide/PPY Polyclonal Antibody

Pancreatic polypeptide/PPY Polyclonal Antibody
  • Pancreatic polypeptide/PPY Polyclonal Antibody
  • Pancreatic polypeptide/PPY Polyclonal Antibody

Price: ¥2100.00 ¥800.00 Inquire

Size:
100 μg 25 μg 1 mg
  • 宿主: Rat
  • 反应性: Human
  • 应用性: ELISA Capture/Detector
Verified Samples
Verified Samples in ELISA: Recombinant Human Pancreatic polypeptide/PPY protein, Human serum, Human plasma
Dilution
ELISA Capture 2-8 μg/mL, ELISA Detector 0.1-0.4 μg/mL
Clonality
Polyclonal
Isotype
Rat IgG
Immunogen
Recombinant Human Pancreatic polypeptide/PPY protein expressed by E.coli
Abbre
Pancreatic polypeptide/PPY
Synonyms
Pancreatic poLypeptide prohormone, PH, Pancreatic poLypeptide Y, Pancreatic poLypeptide, Pancreatic icosapeptide, PPY, PNP
Swissprot
Concentration
1 mg/mL
Storage
Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles.
Buffer
Phosphate buffered solution, pH 7.2, containing 0.05% proclin 300.
Purification Method
Antigen Affinity Purification
Conjugation
Unconjugated
Background
Pancreatic polypeptide (PP),36-amino acid peptide,may function as an important feedback inhibitor of pancreatic secretion after a meal. It arises from both islet and acinar cells of the pancreas. Release of PP by a meal,primarily protein,occurs in a biphasic manner. PP is a negative regulator of energy homeostasis that suppresses food intake and lowers body weight. Similar to other gastrointestinal-derived peptides,PP also modulates gastrointestinal motility and may be involved in the regulation of anxiety. PP,a robust anorexigenic hormone,effectively modulates food intake and energy homeostasis,thus potentially aiding anti-obesity therapeutics. PP is produced in pancreatic islets of Langerhans and released into the circulation after ingestion of a meal. Peripherally administered PP suppresses food intake and gastric emptying. On the other hand,central administration of PP elicits food intake and gastric emptying.
Sandwich ELISA-Recombinant Human Pancreatic polypeptide/PPY protein standard curve.Background subtracted standard curve using Pancreatic polypeptide/PPY antibody(AN000330P)(Capture),Pancreatic polypeptide/PPY antibody(AN000330P)(Detector) in sandwich ELISA.The reference range value for Recombinant Human Pancreatic polypeptide/PPY protein is 62.5-4000 pg/mL.


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