PDCD4 Polyclonal Antibody

Verified Samples in WB:HepG2,Rat thymus,Rat heart
Verified Samples in IHC:Mouse liver,Rat spleen

WB 1:500-1:1000 , IHC 1:100-1:300

Polyclonal

IgG

Recombinant Human Programmed cell death protein 4 protein

PDCD4

Death up-regulated gene protein;Dug;H731;Ma3;MGC33046;MGC33047;Neoplastic transformation inhibitor;Neoplastic transformation inhibitor protein;Nuclear antigen H731;Nuclear antigen H731 like;Nuclear antigen H731 like protein;Nuclear antigen H731-like;PDCD 4;Pdcd4;PDCD4;Programmed cell death 4;programmed cell death 4 (neoplastic transformation inhibitor);Programmed cell death protein 4;Protein 197/15a;Protein MA-3;Tis;Topoisomerase-inhibitor suppressed protein抗体

50,51 kDa

56 kDa

Cytoplasm, Nucleus

0.33 mg/mL

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

PBS with 0.05% Proclin300 and 50% glycerol, pH7.4.

Antigen Affinity Purification

Cancer; Cell Biology; Epigenetics and Nuclear Signaling

Unconjugated

Programmed cell death 4 (Pdcd4) is a novel tumor suppressor that inhibits translation,progression and invasion. It was first identified as being differnetially upregulated during apoptosis. Pdcd4 interferes with the activity of the eukaryotic initiation factor (eIF) 4A by displacing the scaffold protein eIF4G from its binding to the RNA helicase eIF4A.