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PE Anti-Mouse CD62L Antibody[Mel14]

Price: ¥600 ¥420 ¥900

Size:
100Tests 50Tests 100Tests×2
  • 应用性: FCM
  • 亚型: Rat IgG2a, κ
  • 宿主: Rat
Background
CD62L is a 74-95 kD glycoprotein also known as L-selectin, LECAM-1, Ly-22, LAM-1, and MEL-14. It is a member of the selectin family and is expressed on the majority of B and naïve T cells, a subset of memory T cells, monocytes, granulocytes, most thymocytes, and a subset of NK cells. CD62L is important in lymphocyte homing to high endothelial venules (HEV) in peripheral lymph nodes and leukocyte 'rolling' on activated endothelium. CD62L also contributes to neutrophil emigration at inflammatory sites. CD62L is rapidly shed from lymphocytes and neutrophils upon cellular activation and the expression levels of CD62L (in conjunction with other markers) have been used to distinguish naïve, effector, and memory T cells. CD62L has been reported to interact with CD34, GlyCAM-1, and MAdCAM-1.
Alternate Names
L-selectin;Sell;CD62 antigen-like family member L;LAM-1;LECAM1;Lymph node homing receptor;Ly-22; CD62L;Lnhr;Ly22;
Swissprot
Gene ID
Clone No
Host
Rat
Reactivity
Mouse
Application
Isotype
Rat IgG2a, κ
Isotype Control
Conjugation
PE
Conjugation Information
PE is designed to be excited by the Blue (488 nm), Green (532 nm) and Yellow-Green (561 nm) lasers and detected using an optical filter centered near 575 nm (e.g., a 585/42 nm bandpass filter).
Spectrum
Storage Buffer
Phosphate buffered solution, pH 7.2, containing 0.09% sodium azide and 1% BSA.
Storage
This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.
Expiration date
12个月
Shipping
冰袋
C57BL/6 murine splenocytes are stained with PE Anti-Mouse CD62L Antibody (filled gray histogram). Unstained splenocytes (empty black histogram) are used as control.
E-AB-F10110 AF/LE Purified Anti-Mouse CD62L Antibody[Mel14] 500μg , 50μg , 1mg
E-AB-F1011A Purified Anti-Mouse CD62L Antibody[Mel14] 100μg , 25μg
E-AB-F1011B Biotin Anti-Mouse CD62L Antibody[Mel14] 100μg , 25μg
E-AB-F1011C FITC Anti-Mouse CD62L Antibody[Mel14] 100Tests , 50Tests , 100Tests×2
E-AB-F1011E APC Anti-Mouse CD62L Antibody[Mel14] 100Tests , 50Tests , 100Tests×2
E-AB-F1011G PE/Cyanine5 Anti-Mouse CD62L Antibody[Mel14] 100Tests , 50Tests , 100Tests×2
E-AB-F1011H PE/Cyanine7 Anti-Mouse CD62L Antibody[Mel14] 100Tests , 50Tests , 100Tests×2
E-AB-F1011I PE/Cyanine5.5 Anti-Mouse CD62L Antibody[Mel14] 100Tests , 50Tests , 100Tests×2
E-AB-F1011J PerCP/Cyanine5.5 Anti-Mouse CD62L Antibody[Mel14] 100Tests , 50Tests , 100Tests×2
E-AB-F1011L Elab Fluor® 488 Anti-Mouse CD62L Antibody[Mel14] 100Tests , 50Tests , 100Tests×2
E-AB-F1011M Elab Fluor® 647 Anti-Mouse CD62L Antibody[Mel14] 100Tests , 50Tests , 100Tests×2
E-AB-F1011UC FITC Anti-Mouse CD62L Antibody[Mel14] 100μg , 25μg
E-AB-F1011UD PE Anti-Mouse CD62L Antibody[Mel14] 100μg , 25μg
E-AB-F1011UE APC Anti-Mouse CD62L Antibody[Mel14] 100μg , 25μg
E-AB-F1011UG PE/Cyanine5 Anti-Mouse CD62L Antibody[Mel14] 100μg , 25μg
E-AB-F1011UH PE/Cyanine7 Anti-Mouse CD62L Antibody[Mel14] 100μg , 25μg
E-AB-F1011UI PE/Cyanine5.5 Anti-Mouse CD62L Antibody[Mel14] 100μg , 25μg
E-AB-F1011UJ PerCP/Cyanine5.5 Anti-Mouse CD62L Antibody[Mel14] 100μg , 25μg
E-AB-F1011UM Elab Fluor® 647 Anti-Mouse CD62L Antibody[Mel14] 100μg , 25μg

Q1:The difference between CD62L and CD62?

CD62L, CD62E, and CD62P are two immune cell surface molecules that belong to the selectin family. CD62L, also known as L-selectin, is a protein in the integrin family that is expressed primarily on the surface of white blood cells. It is involved in regulating the adhesion and migration of white blood cells, especially in inflammation and immune responses. By binding to its ligand, such as PECAM-1 on vascular endothelial cells, CD62L helps leukocyte to roll out of the circulation and migrate specifically to areas such as inflammation sites or lymph nodes. CD62P, also known as P-selectin, is a adhesion molecule that is expressed primarily on endothelial cells and platelets. In the process of inflammation and thrombosis, CD62P on endothelial cells can be expressed rapidly and bind to ligands (such as PSGL-1) on white blood cells to promote mutual adhesion and activation of white blood cells and platelets. CD62E, also known as E-selectin, is an adhesion molecule that is expressed primarily on endothelial cells.



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