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PE Anti-Mouse CD90.2/Thy1.2 Antibody[30H12]

Price: ¥396 ¥240 ¥684

Size:
100Tests 50Tests 100Tests×2
  • 应用性: FCM
  • 亚型: Rat IgG2b, κ
  • 宿主: Rat
Background
CD90.2 is a 25-35 kD immunoglobulin superfamily member also known as Thy1.2. It is expressed on hematopoietic stem cells and neurons, all thymocytes, and peripheral T cells in Thy1.2 bearing mouse strains (Balb/c, CBA/J, C3H/He, C57BL/-, DBA, NZB/-). CD90.2 is a glycosylphosphatidylinositol (GPI)-anchored membrane glycoprotein involved in signal transduction. CD90.2 is involved in costimulation of lymphocyte proliferation and induction of hematopoietic stem cells differentiation. CD90.2 has been shown to interact with CD45. The 30H12 antibody has been reported to induce Ca2+ flux in thymocytes and, in combination with antibody against the CD3/TCR complex, promote thymocyte apoptosis and inhibit CD3-mediated proliferative responses of mature T lymphocytes.
Alternate Names
Thy-1.2 membrane glycoprotein;Thy1.2;Thy-1.2 antigen;CD90.2;Thy-1.2;
Gene ID
Clone No
Host
Rat
Reactivity
Mouse
Application
Isotype
Rat IgG2b, κ
Isotype Control
Conjugation
PE
Conjugation Information
PE is designed to be excited by the Blue (488 nm), Green (532 nm) and Yellow-Green (561 nm) lasers and detected using an optical filter centered near 575 nm (e.g., a 585/42 nm bandpass filter).
Spectrum
Storage Buffer
Phosphate buffered solution, pH 7.2, containing 0.09% sodium azide and 1% BSA.
Storage
This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.
Expiration date
12个月
Shipping
冰袋
C57BL/6 murine splenocytes are stained with PE Anti-Mouse CD90.2 Antibody (filled gray histogram). Unstained splenocytes (empty black histogram) are used as control.
E-AB-F10940 AF/LE Purified Anti-Mouse CD90.2/Thy1.2 Antibody[30H12] 500μg , 50μg , 1mg
E-AB-F1094A Purified Anti-Mouse CD90.2/Thy1.2 Antibody[30H12] 100μg , 25μg
E-AB-F1094B Biotin Anti-Mouse CD90.2/Thy1.2 Antibody[30H12] 100μg , 25μg
E-AB-F1094C FITC Anti-Mouse CD90.2/Thy1.2 Antibody[30H12] 100Tests , 50Tests , 100Tests×2
E-AB-F1094E APC Anti-Mouse CD90.2/Thy1.2 Antibody[30H12] 100Tests , 50Tests , 100Tests×2
E-AB-F1094F PerCP Anti-Mouse CD90.2/Thy1.2 Antibody[30H12] 100Tests , 50Tests , 100Tests×2
E-AB-F1094G PE/Cyanine5 Anti-Mouse CD90.2/Thy1.2 Antibody[30H12] 100Tests , 50Tests , 100Tests×2
E-AB-F1094H PE/Cyanine7 Anti-Mouse CD90.2/Thy1.2 Antibody[30H12] 100Tests , 50Tests , 100Tests×2
E-AB-F1094I PE/Cyanine5.5 Anti-Mouse CD90.2/Thy1.2 Antibody[30H12] 100Tests , 50Tests , 100Tests×2
E-AB-F1094J PerCP/Cyanine5.5 Anti-Mouse CD90.2/Thy1.2 Antibody[30H12] 100Tests , 50Tests , 100Tests×2
E-AB-F1094L Elab Fluor® 488 Anti-Mouse CD90.2/Thy1.2 Antibody[30H12] 100Tests , 50Tests , 100Tests×2
E-AB-F1094M Elab Fluor® 647 Anti-Mouse CD90.2/Thy1.2 Antibody[30H12] 100Tests , 50Tests , 100Tests×2
E-AB-F1094Q Elab Fluor® Violet 450 Anti-Mouse CD90.2/Thy1.2 Antibody[30H12] 100Tests , 50Tests , 100Tests×2
E-AB-F1094UC FITC Anti-Mouse CD90.2/Thy1.2 Antibody[30H12] 100μg , 25μg
E-AB-F1094UD PE Anti-Mouse CD90.2/Thy1.2 Antibody[30H12] 100μg , 25μg
E-AB-F1094UE APC Anti-Mouse CD90.2/Thy1.2 Antibody[30H12] 100μg , 25μg
E-AB-F1094UF PerCP Anti-Mouse CD90.2/Thy1.2 Antibody[30H12] 100μg , 25μg
E-AB-F1094UG PE/Cyanine5 Anti-Mouse CD90.2/Thy1.2 Antibody[30H12] 100μg , 25μg
E-AB-F1094UH PE/Cyanine7 Anti-Mouse CD90.2/Thy1.2 Antibody[30H12] 100μg , 25μg
E-AB-F1094UI PE/Cyanine5.5 Anti-Mouse CD90.2/Thy1.2 Antibody[30H12] 100μg , 25μg
E-AB-F1094UJ PerCP/Cyanine5.5 Anti-Mouse CD90.2/Thy1.2 Antibody[30H12] 100μg , 25μg
E-AB-F1094UL Elab Fluor® 488 Anti-Mouse CD90.2/Thy1.2 Antibody[30H12] 100μg , 25μg
E-AB-F1094UM Elab Fluor® 647 Anti-Mouse CD90.2/Thy1.2 Antibody[30H12] 100μg , 25μg
E-AB-F1094UQ Elab Fluor® Violet 450 Anti-Mouse CD90.2/Thy1.2 Antibody[30H12] 100μg , 25μg

Q1:What is the difference between Mouse CD90 and CD90.1 and CD90.2?

CD90, also known as Thy1 (thymus cell antigen 1), is a mouse immune cell surface molecule. In mice, there are two main subtypes of CD90: CD90.1 and CD90.2. The difference between the two subtypes is due to allelic differences on the loci. CD90.1 and CD90.2 are expression variants controlled by different gene alleles. For example, in C57BL/6 mice, CD90.1 expression is regulated by the Ly5.2 locus, while CD90.2 is controlled by the Ly5.1 locus. Due to the differences in the loci of CD90.1 and CD90.2, these subtypes can be used for labeling in experiments to distinguish cells of different origin. By introducing the allele of CD90.1 or CD90.2, cells can be genetically labeled to identify, trace and quantitatively analyze cells of specific origin. CD90 can be expressed on hematopoietic stem cells, neurons, all thymic cells, and peripheral T cells. The mouse strains expressing CD90.1 included AKR, BDP, MA/MyJ, etc., and more mouse strains expressing CD90.2 included Balb/c, CBA/J, C3H/He, C57BL/-, DBA, NZB/-, etc.



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