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PE Anti-Rat CD44H Antibody[OX-49]

Price: ¥2640 ¥864

Size:
100μg 25μg
  • 应用性: FCM
  • 亚型: Mouse IgG2a, κ
  • 宿主: Mouse
Background
CD44 is an 80-95 kD cell surface glycoprotein. It is expressed on all leukocytes, endothelial cells, hepatocytes, and mesenchymal cells. It is up-regulated when T cells and B cells are activated. It was reported that CD44 is a valuable marker for memory T cells. CD44 is an adhesion molecule involved in leukocyte adhesion and homing to lymphoid organs. The OX-49 antibody reacts with CD44H (known as CD44s) expressed on most leukocytes, except for a subset of B lymphocytes. The epitope recognized by OX-49 antibody has been mapped to a region on both the standard, CD44s, and the splice variant, CD44v, isoforms of CD44. However it was reported that OX-49 antibody cannot detect the CD44V isoform, possibly due to conformational changes in the epitope.
Alternate Names
Pgp-1; H-CAM; CD44s;CD44H;
Swissprot
Gene ID
Clone No
Host
Mouse
Reactivity
Rat
Application
Isotype
Mouse IgG2a, κ
Isotype Control
Conjugation
PE
Conjugation Information
PE is designed to be excited by the Blue (488 nm), Green (532 nm) and Yellow-Green (561 nm) lasers and detected using an optical filter centered near 575 nm (e.g., a 585/42 nm bandpass filter).
Spectrum
Storage Buffer
Phosphate buffered solution, pH 7.2, containing 0.09% sodium azide and 1% BSA.
Storage
This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.
Expiration date
12个月
Shipping
冰袋
Rat splenocytes are stained with PE Anti-Rat CD44H Antibody (filled gray histogram). Unstained splenocytes (empty black histogram) are used as control.
E-AB-F1225C FITC Anti-Rat CD44H Antibody[OX-49] 100Tests , 50Tests , 100Tests×2
E-AB-F1225D PE Anti-Rat CD44H Antibody[OX-49] 100Tests , 50Tests , 100Tests×2
E-AB-F1225E APC Anti-Rat CD44H Antibody[OX-49] 100Tests , 50Tests , 100Tests×2
E-AB-F1225G PE/Cyanine5 Anti-Rat CD44H Antibody[OX-49] 100Tests , 50Tests , 100Tests×2
E-AB-F1225H PE/Cyanine7 Anti-Rat CD44H Antibody[OX-49] 100Tests , 50Tests , 100Tests×2
E-AB-F1225J PerCP/Cyanine5.5 Anti-Rat CD44H Antibody[OX-49] 100Tests , 50Tests , 100Tests×2
E-AB-F1225UC FITC Anti-Rat CD44H Antibody[OX-49] 100μg , 25μg
E-AB-F1225UE APC Anti-Rat CD44H Antibody[OX-49] 100μg , 25μg
E-AB-F1225UG PE/Cyanine5 Anti-Rat CD44H Antibody[OX-49] 100μg , 25μg
E-AB-F1225UH PE/Cyanine7 Anti-Rat CD44H Antibody[OX-49] 100μg , 25μg
E-AB-F1225UJ PerCP/Cyanine5.5 Anti-Rat CD44H Antibody[OX-49] 100μg , 25μg

Q1:Is CD44H CD44?

Yes, it is. CD44H is one of the common names for CD44. CD44 (cluster of differentiation 44) is an immune cell surface molecule, also known as Hyaluronate receptor. The CD44 protein is diverse through the presence of multiple variant shear forms (isoforms). Among them, CD44H is the standard form of CD44, which is the main variant shear form of CD44. CD44H interacts with components of the extracellular matrix, such as hyaluronan, and is involved in biological processes such as cell adhesion, migration, and signaling. CD44H is widely expressed in many cell types and has important functions in immune cells, tumor cells, and stem cells. It is important to note that different CD44 variant cut forms may have different functions and expression patterns. Therefore, in specific studies or experiments, it may be necessary to further distinguish and study specific CD44 variant shear forms (such as CD44v6, CD44s, etc.).



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