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PE/Cyanine7 Anti-Human CD74 Antibody[LN2]

Price: ¥3420 ¥1380 ¥5100

Size:
100Tests 20Tests 100Tests×2
  • 应用性: FCM
  • 亚型: Mouse IgG1, κ
  • 宿主: Mouse
Background
CD74 is a type II transmembrane glycoprotein also known as MHC class II associated invariant chain, invariant chain, Ii, MHC class II chaperone, and MIF receptor. CD74 exists in four isoforms with molecular masses of 33, 35, 41, and 43 kD, depending on genetic splicing. CD74 is primarily expressed on antigen presenting cells, including B cells, monocytes/macrophages, dendritic cells, and Langerhans cells. It is also expressed by activated T cells and activated endothelial and epithelial cells as well as carcinomas of lung, renal, gastric and thymic origin. The primary function of CD74 is intracellular sorting of MHC class II molecules and regulation of exogenous peptide loading onto MHC class II. It is also involved in the modulation of B cell differentiation and positive selection of CD4+ T cells. It has been reported that CD74 binds MIF (macrophage migration inhibitory factor) and signals through CD44 to regulate innate and adaptive immunity. It is also reported that H. pylori infection occurs through urease B binding of CD74 on gastric epithelial cells, inducing gastric epithelial cell apoptosis, NF-κB activation, and IL-8 production.
Alternate Names
HLA class II histocompatibility antigen gamma chain;CD74;Ia antigen-associated invariant chain;Ii;p33;DHLAG;
Swissprot
Gene ID
Clone No
Host
Mouse
Reactivity
Human
Application
Isotype
Mouse IgG1, κ
Isotype Control
Conjugation
PE/Cyanine 7
Conjugation Information
PE/Cyanine7 is designed to be excited by the Blue (488 nm), Green (532 nm) and yellow-green (561 nm) lasers and detected using an optical filter centered near 775 nm (e.g., a 780/60 nm bandpass filter).
Spectrum
Storage Buffer
Phosphate buffered solution, pH 7.2, containing 0.09% sodium azide and 1% BSA.
Storage
This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.
Expiration date
12个月
Shipping
冰袋
Human peripheral blood lymphocytes are stained with Elab Fluor® 488 Anti-Human CD19 Antibody and PE/Cyanine7 Anti-Human CD74 Antibody[LN2] (Left). Lymphocytes are stained with Elab Fluor® 488 Anti-Human CD19 Antibody and PE/Cyanine7 Mouse IgG1, κ Isotype Control (Right).
E-AB-F1072A Purified Anti-Human CD74 Antibody[LN2] 100μg , 25μg
E-AB-F1072B Biotin Anti-Human CD74 Antibody[LN2] 100μg , 25μg
E-AB-F1072C FITC Anti-Human CD74 Antibody[LN2] 100Tests , 20Tests , 100Tests×2
E-AB-F1072D PE Anti-Human CD74 Antibody[LN2] 100Tests , 20Tests , 100Tests×2
E-AB-F1072E APC Anti-Human CD74 Antibody[LN2] 100Tests , 20Tests , 100Tests×2
E-AB-F1072G PE/Cyanine5 Anti-Human CD74 Antibody[LN2] 100Tests , 20Tests , 100Tests×2
E-AB-F1072I PE/Cyanine5.5 Anti-Human CD74 Antibody[LN2] 100Tests , 20Tests , 100Tests×2
E-AB-F1072J PerCP/Cyanine5.5 Anti-Human CD74 Antibody[LN2] 100Tests , 20Tests , 100Tests×2
E-AB-F1072L Elab Fluor® 488 Anti-Human CD74 Antibody[LN2] 100Tests , 20Tests , 100Tests×2
E-AB-F1072M Elab Fluor® 647 Anti-Human CD74 Antibody[LN2] 100Tests , 20Tests , 100Tests×2
E-AB-F1072P PE/Elab Fluor® 594 Anti-Human CD74 Antibody[LN2] 100Tests , 20Tests , 100Tests×2


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