PFKFB1 Polyclonal Antibody
Price:
Size:
200μL
120μL
60μL
20μL
- 宿主: Rabbit
- 反应性: Human;Mouse;Rat
- 应用性: IHC
Verified Samples |
Verified Samples in IHC:Human liver cancer,Human brain |
Dilution | IHC 1:50-1:200 |
Clonality | Polyclonal |
Isotype | IgG |
Immunogen | Synthetic peptide of human PFKFB1 |
Abbre | PFKFB1 |
Synonyms | F6PK;HL2K;PFRX抗体 |
Swissprot | |
Cellular Localization | Cytosol,6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex,cytosol |
Concentration | 0.5 mg/mL |
Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
Buffer | PBS with 0.05% sodium azide and 50% glycerol, PH7.4 |
Purification Method | Affinity purification |
Research Areas | Cancer; Cardiovascular; Metabolism; Neuroscience; Signal Transduction |
Conjugation | Unconjugated |
Background | This gene encodes a member of the family of bifunctional 6-phosphofructo-2-kinase:fructose-2,6-biphosphatase enzymes. The enzyme forms a homodimer that catalyzes both the synthesis and degradation of fructose-2,6-biphosphate using independent catalytic domains. Fructose-2,6-biphosphate is an activator of the glycolysis pathway and an inhibitor of the gluconeogenesis pathway. Consequently, regulating fructose-2,6-biphosphate levels through the activity of this enzyme is thought to regulate glucose homeostasis. Multiple alternatively spliced transcript variants have been found for this gene. |
Immunohistochemistry of paraffin-embedded Human liver cancer tissue using PFKFB1 Polyclonal Antibody at dilution 1:60
Immunohistochemistry of paraffin-embedded Human brain tissue using PFKFB1 Polyclonal Antibody at dilution 1:60
E-IR-R217 | 2-step plus Poly-HRP Anti Mouse/Rabbit IgG Detection System (with DAB solution) | 18mL , 6mL , 3mL |
E-IR-R220 | Super PlusTM Highly Sensitive and Rapid Immunohistochemical Kit (pH9.0) | 10mL , 3mL |
E-IR-R221 | Super PlusTM Highly Sensitive and Rapid Immunohistochemical Kit (pH6.0) | 10mL , 3mL |
E-IR-R304A | Western Blot Detection Kit | 50Assays |
E-IR-R304B | High Accuracy and Absorbability Western Blot Detection Kit | 50Assays |