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PFKFB1 Polyclonal Antibody

Price: ¥2365 ¥1640 ¥1010 ¥420

Size:
200μL 120μL 60μL 20μL
  • 宿主: Rabbit
  • 反应性: Human;Mouse;Rat
  • 应用性: IHC
Verified Samples
Verified Samples in IHC:Human liver cancer,Human brain
Dilution
IHC 1:50-1:200
Clonality
Polyclonal
Isotype
IgG
Immunogen
Synthetic peptide of human PFKFB1
Abbre
PFKFB1
Synonyms
F6PK;HL2K;PFRX抗体
Swissprot
Cellular Localization
Cytosol,6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex,cytosol
Concentration
0.5 mg/mL
Storage
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Purification Method
Affinity purification
Research Areas
Cancer; Cardiovascular; Metabolism; Neuroscience; Signal Transduction
Conjugation
Unconjugated
Background
This gene encodes a member of the family of bifunctional 6-phosphofructo-2-kinase:fructose-2,6-biphosphatase enzymes. The enzyme forms a homodimer that catalyzes both the synthesis and degradation of fructose-2,6-biphosphate using independent catalytic domains. Fructose-2,6-biphosphate is an activator of the glycolysis pathway and an inhibitor of the gluconeogenesis pathway. Consequently, regulating fructose-2,6-biphosphate levels through the activity of this enzyme is thought to regulate glucose homeostasis. Multiple alternatively spliced transcript variants have been found for this gene.
Immunohistochemistry of paraffin-embedded Human liver cancer tissue using PFKFB1 Polyclonal Antibody at dilution 1:60
Immunohistochemistry of paraffin-embedded Human brain tissue using PFKFB1 Polyclonal Antibody at dilution 1:60


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