Phospho-CREB1 (Ser133) Polyclonal Antibody

Verified Samples in WB:MCF-7,A549,K562,HEK293
Verified Samples in IHC:Human uterus
Verified Samples in IF:Mouse lung

WB 1:500-1:2000, IHC 1:100-1:300, IF 1:100-1:300

Polyclonal

IgG

Synthesized peptide derived from human CREB-1 around the phosphorylation site of Ser133

CREB-1 (phospho Ser133)

Active transcription factor CREB;cAMP response element binding protein 1;cAMP response element binding protein;cAMP responsive element binding protein 1;cAMP-responsive element-binding protein 1;CREB;CREB-1;CREB1;CREB1;Cyclic AMP-responsive element-binding protein 1;MGC9284;OTTHUMP00000163864;OTTHUMP00000163865;OTTHUMP00000206660;OTTHUMP00000206662;OTTHUMP00000206667;Transactivator protein抗体

37kDa

37kDa

Nucleus.

1 mg/mL

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

PBS with 0.02% sodium azide, 0.5% protective protein and 50% glycerol, pH7.4

Affinity purification

Cancer; Epigenetics and Nuclear Signaling; Immunology

Unconjugated

This protein binds the cAMP response element (CRE), a sequence present in many viral and cellular promoters. CREB stimulates transcription on binding to the CRE. Transcription activation is enhanced by the TORC coactivators which act independently of Ser-133 phosphorylation. Implicated in synchronization of circadian rhythmicity.