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Progranulin/PGRN Polyclonal Antibody(Capture/Detector)

Progranulin/PGRN Polyclonal Antibody(Capture/Detector)
  • Progranulin/PGRN Polyclonal Antibody(Capture/Detector)
  • Progranulin/PGRN Polyclonal Antibody(Capture/Detector)

Price: ¥2100.00 ¥800.00 Inquire

Size:
100 μg 25 μg 1 mg
  • 宿主: Rabbit
  • 反应性: Human
  • 应用性: ELISA Capture/Detector
Verified Samples
Verified Samples in ELISA: Recombinant Human Progranulin/PGRN protein, Human serum, Human plasma
Dilution
ELISA Capture 2-8 μg/mL, ELISA Detector 0.1-0.4 μg/mL
Clonality
Polyclonal
Isotype
Rabbit IgG
Immunogen
Recombinant Human Progranulin/PGRN protein expressed by Mammalian
Abbre
Progranulin/PGRN
Synonyms
proepithelin, PC cell-derived growth factor, 
Swissprot
Concentration
1 mg/mL
Storage
Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles.
Buffer
Phosphate buffered solution, pH 7.2, containing 0.05% proclin 300.
Purification Method
Antigen Affinity Purification
Research Areas
Cancer, Immunology, Neuroscience, Signal transduction
Conjugation
Unconjugated
Background
Granulins are a family of secreted, glycosylated peptides that are cleaved from a single precursor protein with 7.5 repeats of a highly conserved 12-cysteine granulin/epithelin motif. The 88 kDa precursor protein, progranulin, is also called proepithelin and PC cell-derived growth factor. Cleavage of the signal peptide produces mature granulin which can be further cleaved into a variety of active, 6 kDa peptides. These smaller cleavage products are named granulin A, granulin B, granulin C, etc. Epithelins 1 and 2 are synonymous with granulins A and B, respectively. Both the peptides and intact granulin protein regulate cell growth. However, different members of the granulin protein family may act as inhibitors, stimulators, or have dual actions on cell growth. Granulin family members are important in normal development, wound healing, and tumorigenesis.
Sandwich ELISA-Recombinant Human Progranulin/PGRN protein standard curve.Background subtracted standard curve using Progranulin/PGRN antibody(AN000780P)(Capture),Progranulin/PGRN antibody(AN000780P)(Detector) in sandwich ELISA.The reference range value for Recombinant Human Progranulin/PGRN protein is 62.5-4000 pg/mL.


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