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Purified Anti-Human CD279/PD-1 Antibody[J110]

Price: ¥712 ¥288

Size:
100μg 25μg
  • 应用性: FCM
  • 亚型: Mouse IgG1, κ
  • 宿主: Mouse
Background
Programmed cell death 1 (PD-1), also known as CD279, is a 55 kD member of the immunoglobulin superfamily. CD279 contains the immunoreceptor tyrosine-based inhibitory motif (ITIM) in the cytoplasmic region and plays a key role in peripheral tolerance and autoimmune disease. CD279 is expressed predominantly on activated T cells, B cells, and myeloid cells. PD-L1 and PD-L2 are ligands of CD279 (PD-1) and are members of the B7 gene family. Evidence suggests overlapping functions for these two PD-1 ligands and their constitutive expression on some normal tissues and upregulation on activated antigen-presenting cells. Interaction of CD279 ligands results in inhibition of T cell proliferation and cytokine secretion.
Alternate Names
PDCD1;PD1;Protein PD-1;hPD-1;
Swissprot
Gene ID
Clone No
Host
Mouse
Reactivity
Human
Application
Isotype
Mouse IgG1, κ
Isotype Control
Conjugation
Unconjugated
Storage Buffer
Phosphate buffered solution, pH 7.2, containing 0.09% sodium azide.
Storage
This product can be stored at 2-8°C for 12 months. Do not freeze.
Expiration date
12个月
Shipping
冰袋
E-AB-F12130 AF/LE Purified Anti-Human CD279/PD-1 Antibody[J110] 500μg , 50μg , 1mg


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