RBP3 Polyclonal Antibody
Price:
Size:
200μL
120μL
60μL
20μL
- 宿主: Rabbit
- 反应性: Mouse;Rat
- 应用性: IHC
Verified Samples |
Verified Samples in IHC:Mouse retina,Rat retina |
Dilution | IHC 1:50-1:100 |
Clonality | Polyclonal |
Isotype | IgG |
Immunogen | Recombinant human Retinol-binding protein 3 protein |
Abbre | RBP3 |
Synonyms | D10S64;D10S65;D10S66;Interphotoreceptor retinoid binding protein;Interphotoreceptor retinoid-binding protein;Interstitial retinol binding protein;Interstitial retinol-binding protein;IRBP;RBP 3;rbp3;RBPI;RET3;Retinol binding protein 3;Retinol binding protein 3 interstitial;Retinol-binding protein 3;RP66抗体 |
Swissprot | |
Cellular Localization | Secreted>extracellular space>extracellular matrix>interphotoreceptor matrix. Interphotoreceptor matrix that permeates the space between the retina and the contiguous layer of pigment epithelium cells. |
Concentration | 2mg/mL |
Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
Buffer | PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Purification Method | Affinity purification |
Research Areas | Neuroscience |
Conjugation | Unconjugated |
Background | Interphotoreceptor retinol-binding protein is a large glycoprotein known to bind retinoids and found primarily in the interphotoreceptor matrix of the retina between the retinal pigment epithelium and the photoreceptor cells. It is thought to transport retinoids between the retinal pigment epithelium and the photoreceptors, a critical role in the visual process.The human IRBP gene is approximately 9.5 kbp in length and consists of four exons separated by three introns. The introns are 1.6-1.9 kbp long. The gene is transcribed by photoreceptor and retinoblastoma cells into an approximately 4.3-kilobase mRNA that is translated and processed into a glycosylated protein of 135,000 Da. The amino acid sequence of human IRBP can be divided into four contiguous homology domains with 33-38% identity, suggesting a series of gene duplication events. In the gene, the boundaries of these domains are not defined by exon-intron junctions, as might have been expected. The first three homology domains and part of the fourth are all encoded by the first large exon, which is 3,180 base pairs long. The remainder of the fourth domain is encoded in the last three exons, which are 191, 143, and approximately 740 base pairs long, respectively. |
Immunohistochemistry of paraffin-embedded Mouse retina using RBP3 Polyclonal Antibody at dilution of 1:50
Immunohistochemistry of paraffin-embedded Rat retina using RBP3 Polyclonal Antibody at dilution of 1:50
E-IR-R217 | 2-step plus Poly-HRP Anti Mouse/Rabbit IgG Detection System (with DAB solution) | 18mL , 6mL , 3mL |
E-IR-R220 | Super PlusTM Highly Sensitive and Rapid Immunohistochemical Kit (pH9.0) | 10mL , 3mL |
E-IR-R221 | Super PlusTM Highly Sensitive and Rapid Immunohistochemical Kit (pH6.0) | 10mL , 3mL |
E-IR-R304A | Western Blot Detection Kit | 50Assays |
E-IR-R304B | High Accuracy and Absorbability Western Blot Detection Kit | 50Assays |