Recombinant SARS-CoV-2 NSP10 Protein (His Tag)

SARS-CoV 2 nsp10;SARS-CoV 2 Growth factor-like peptide;SARS-CoV 2 GFL

E.coli

Ala1-Gln139

YP_009725306.1

SARS-CoV-2

17.9 kDa

18 kDa

N-His

> 80 % as determined by reducing SDS-PAGE.

< 1.0 EU per μg of the protein as determined by the LAL method.

Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.

This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.

Supplied as a 0.2 μM filtered solution of PBS, 10% Glycerol, pH 7.4.

Not Applicable

Nsp10 have shown that it is a 15-kDa protein of unknown function that has been shown to interact with itself, nsp1, and nsp7. It colocalizes with N to sites of viral replication and is essential for replication. It plays a pivotal role in viral transcription by stimulating both nsp14 3'-5' exoribonuclease and nsp16 2'-O-methyltransferase activities. Therefore plays an essential role in viral mRNAs cap methylation. Nsp10 is a critical regulator of coronavirus RNA synthesis and may play an important role in polyprotein processing.